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BIBTEX RIS

An expedient stereoselective access to (Z)-2-fluoroalkenoates

1993; Elsevier BV; Volume: 34; Issue: 43 Linguagem: Inglês

10.1016/s0040-4039(00)91826-4

ISSN

1873-3581

Autores

Denis Clemenceau, Jack Cousseau,

Tópico(s)

Inorganic Fluorides and Related Compounds

Resumo

The reaction between an aldehyde R-CHO and diethyl 2-oxo-3-fluorobutan-1,4-dioate as its sodium salt EtO2C-CO-CF-CO2Et−, Na+ mainly leads in THF to (Z)-2-fluoroalkenoates R-CHCF-CO2Et (Z/E& > -80/20), the Z-stereoselectivity depending on the bulk of the R group.

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