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Two sesquiterpene isocyanides and a sesquiterpene thiocyanate from the marine sponge Acanthella cf. cavernosa and the Nudibranch Phyllidia ocellata

1992; Elsevier BV; Volume: 33; Issue: 45 Linguagem: Inglês

10.1016/s0040-4039(00)61785-9

1873-3581

Nobuhiro Fusetani, H.J. Wolstenholme, Katsumi Shinoda, Naoki Asai, Shigeki Matsunaga, Hiroyuki Onuki, Hiroshi Hirota,

Chemical synthesis and alkaloids

Three new antifungal sesquiterpenoids, cavernoisonitrile (1), cavernothiocyanate (2), and 10α-isocyano-4-amorphene (3), have been isolated from the marine sponge Acanthella cf. cavernosa, and their structures were elucidated on the basis of spectroscopic data. The nudibranch Phyllidia ocellata also contained 2 and 3.