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Oligomeric flavanoids. Part 2. The first profisetinidins with dihydroflavonol constituent units

1988; Issue: 9 Linguagem: Inglês

10.1039/p19880002567

2050-8255

Johannes C. S. Malan, Desmond A. Young, Jacobus A. Steenkamp, Daneel Ferreira,

Cancer Treatment and Pharmacology

The range of naturally occurring profisetinidins is extended by characterization of the first (–)-fisetinidol(–)-robinetinidol dimer and of a novel analogue based on the 3-O-galloyl ester of (+)-catechin. These metabolites are accompanied by (–)-fisetinidol-(4α,2′)-robinetin, (–)-fisetinidol-(4α,6)-(+)-taxifolin, and (–)-fisetinidol-(4α,6)- and (4β,6)-(+)-ampelopsins. The latter three compounds are representative of the first natural profisetinidins with dihydroflavonols as constituent units.