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Autometallographic demonstration of mercury in rat molars

1994; Wiley; Volume: 102; Issue: 1 Linguagem: Inglês

10.1111/j.1600-0722.1994.tb01158.x

1600-0722

Rune Eide, Jørgen Drasbæk Schiønning, Roger Bjugn, Gro Ramsten Wesenberg, Gisle Fosse,

Trace Elements in Health

Male, adult Wistar rats were exposed to 500 μg/m 3 mercury vapor 6 h per day, 5 days a week for 4 wk. They were subsequently killed by transcardial perfusion. The molars were extracted, demineralized, and embedded in resin before section‐ing. Autometallographic development was performed according to the method of D anscher & M öller ‐M adsen . Mercury deposits were found in small amounts in several areas of the pulp, but with larger accumulations of grains in relation to odontoblasts. Mercury also could be seen in odontoblastic processes in the dentin and predentin. Our conclusion is therefore that systemic uptake of mercury vapor leads to accumulation of mercury in the odontoblasts and that the mercury may be transported into the dentin tubules in the odontoblastic process.