Glucagon‐producingneuroendocrine tumour associated with hypoaminoacidaemia and skin lesions
2000; Wiley; Volume: 41; Issue: 9 Linguagem: Inglês
10.1111/j.1748-5827.2000.tb03232.x
ISSN1748-5827
AutoresKarin Allenspach, Pierre Arnold, T. Gnus, B. Hauser, C. Michael Wolff, Charlotte Eberle, P. Kommlnoth,
Tópico(s)Lung Cancer Research Studies
ResumoA nine-year-old neutered female crossbred Bernese mountain dog was diagnosed with superficial necrolytic dermatitis and a glucagon-producing islet cell tumour. Laboratory findings included hyperglucagonaemia and hypoaminoacidaemia. The dog was euthanased because of progression of the disease, and necropsy revealed liver metastases of a neuroendocrine carcinoma with immunohistochemical expression of glucagon and somatostatin. This report represents a case of canine glucagonoma syndrome; the previously reported cases in dogs are also briefly described.
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