THE HUMAN ACETYLCHOLINE RECEPTOR ANTIBODY: STUDIES OF KINETIC AND BIOCHEMICAL PROPERTIES AND THE REACTION WITH ANTI‐IDIOTYPIC ANTIBODIES*
1981; Wiley; Volume: 377; Issue: 1 Linguagem: Inglês
10.1111/j.1749-6632.1981.tb33728.x
ISSN1749-6632
Autores Tópico(s)Neuroscience and Neural Engineering
ResumoAnnals of the New York Academy of SciencesVolume 377, Issue 1 p. 125-142 THE HUMAN ACETYLCHOLINE RECEPTOR ANTIBODY: STUDIES OF KINETIC AND BIOCHEMICAL PROPERTIES AND THE REACTION WITH ANTI-IDIOTYPIC ANTIBODIES* Ann Kari Lefvert, Ann Kari Lefvert Department of Clinical Chemistry Karolinska Institute Huddinge University Hospital S-141 86 Huddinge, SwedenSearch for more papers by this author Ann Kari Lefvert, Ann Kari Lefvert Department of Clinical Chemistry Karolinska Institute Huddinge University Hospital S-141 86 Huddinge, SwedenSearch for more papers by this author First published: December 1981 https://doi.org/10.1111/j.1749-6632.1981.tb33728.xCitations: 20 * This work was supported by a grant from the Medical Faculty of the Karolinska Institute, a grant from the Swedish Medical Research Council, and a grant from the Swedish Society of Medical Sciences. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Lefvert, A. K., K. Bergström, G. Matell, P. O. Osterman & R. Pirskanen 1978. Determination of acetylcholine receptor antibodies in myasthenia gravis: clinical usefulness and pathogenetic implications. J. Neurol. Neurosurg. Psychiat. 41: 394–403. 10.1136/jnnp.41.5.394 PubMedWeb of Science®Google Scholar 2 Vincent, A. 1980. Immunology of acetylcholine receptors in relation to myasthenia gravis. Physiol. Rev. 60: 756–824. 10.1152/physrev.1980.60.3.756 CASPubMedWeb of Science®Google Scholar 3 Lefvert, A. K. & G. Matell. 1979. Thoracic duct lymph drainage in myasthenia gravis: clinical effect and kinetic studies of the acetylcholine receptor antibody. In Plasmapheresis and the lmmunobiology of Myasthenia Gravis. P. C. Dau, Ed.: 151–160. Houghton Mifflin, Boston , Mass . Google Scholar 4 Lefvert, A. K. 1978. Immunoglobulins in myasthenia gravis: kinetic properties of the acetylcholine receptor antibody studied during lymph drainage. J. Clin. Exp. Immunol. 34: 111–117. CASPubMedWeb of Science®Google Scholar 5 Andersen, S. B. & N. Rossing. 1967. Metabolism of albumin and yglobulin during albumin infusions and during plasmapheresis. Scand. J. Clin. Lab. Invest. 20: 183–184. 10.3109/00365516709076941 Web of Science®Google Scholar 6 Bystryn, J-C., M. W. Graf & J. W. Uhr. 1970. Regulation of antibody formation by serum antibody. II. Removal of specific antibody by means of exchange transfusion. J. Exp. Med.. 132: 1279–1287. 10.1084/jem.132.6.1279 CASPubMedWeb of Science®Google Scholar 7 Branda, R. F., C. F. Moldow, I. J. Mccullough & H. S. Jacob. 1970. Plasma exchange in the treatment of immune diseases. Transfusion 15: 570–576. 10.1046/j.1537-2995.1975.15676082232.x PubMedWeb of Science®Google Scholar 8 Waldmann, T. A. & W. Strober. 1969. Metabolism of immunoglobulins. Progr. Allergy 13: 1–110. Karger, Basel . Web of Science®Google Scholar 9 Morell, A., F. Skvaril & S. Barandun. 1975. IgG Subklassen der Mensch- lichen Immunoglobuline. Immunochemische, Genetische, Biologische und Klinische Aspecte. S. Karger. Basel . Google Scholar 10 Lefvert, A. K., S. Cuenoud & B. W. Fulpius. 1981. Binding properties and subclass distribution of anti-acetylcholine receptor antibodies in myasthenia gravis. J. Neuroimmun. 1: 125–135. 10.1016/0165-5728(81)90015-1 CASPubMedWeb of Science®Google Scholar 11 Lefvert, A. K. & K. Bergstrom. 1977. Immunoglobulins in myasthenia gravis: effect of human lymph IgG3 and F(ab′)2 fragments on a cholinergic receptor preparation from Torpedo rnarmorata. Eur. J. Clin. Invest. 7: 115–119. 10.1111/j.1365-2362.1977.tb01582.x CASPubMedWeb of Science®Google Scholar 12 Lefvert, A. K. & K. Bergstrom. 1978. Acetylcholine receptor antibodies in myasthenia gravis: Purification and characterization. Scand. J. Immunol. 8: 525–533. 10.1111/j.1365-3083.1978.tb00552.x CASPubMedWeb of Science®Google Scholar 13 Perutz, E. M., W. J. Yount, M. Newell & P. D. Utsinger. 1973. Immuno-globulin classes and IgG subclasses of human antinuclear antibodies. A correlation of complement fixation and the nephritis of systemic lupus erythematosus. Clin. Immunol. Immunopathol. 2: 98–113. 10.1016/0090-1229(73)90040-8 Web of Science®Google Scholar 14 Lindstrom, J. 1976. Immunological studies of acetylcholine receptors. J. Supramol. Structure. 4: 389–403. 10.1002/jss.400040310 CASPubMedWeb of Science®Google Scholar 15 Aharonow, A., O. Abramsky, R. Tarrab-Hazdai & S. Fuchs. 1975. Humoral antibodies to acetylcholine receptors in patients with myasthenia gravis. Lancet ii: 340–342. 10.1016/S0140-6736(75)92779-8 CASGoogle Scholar 16 McAdams, M. W. & A. D. Roses. 1979. Comparison of antigenic sources for acetylcholine receptor antibody assays in myasthenia gravis. Ann. Neurol. 8: 61–66. 10.1002/ana.410080109 Web of Science®Google Scholar 17 Dau, P. C., C. S. Yano & S. J. Ettinger. 1979. Antibody towards the acetylcholine receptor in canine and human myasthenia gravis: differential crossreactivity with human and rabbit receptor. Neurol. 29: 1065–1068. 10.1212/WNL.29.7.1065 CASPubMedWeb of Science®Google Scholar 18 Lefvert, A. K. 1978. Acetylcholine receptor antibodies in myasthenia gravis. Thesis. Stockholm . Google Scholar 19 Almon, R. R. & S. H. Appel. 1975. Interaction of myasthenic serum globulin with the acetylcholine receptor. Biochim. Biophys. Acta. 393: 66–77. 10.1016/0005-2795(75)90217-2 CASPubMedWeb of Science®Google Scholar 20 Vincent, A. & J. Newsom-Davis. 1979. α-bungarotoxin and anti-acetylcholine receptor antibody binding to the human acetylcholine receptor. In Advances in Cytopharmacology. B. Ceccarelli & F. Clementi, Eds. 3. Raven Press, New York , NY . Google Scholar 21 Lefvert, A. K. 1980. Differences in the interaction of acetylcholine receptor antibodies with receptor from normal, denervated and myasthenic human skeletal muscle J. Neurol. Neurosurg. Psychiat. In press. Google Scholar 22 Schwartz, M., D. Novic, D. Givol & S. Fuchs. 1978. Induction of anti-idiotypic antibodies by immunization with syngeneic spleen cells educated with acetylcholine receptor. Nature (Lond.) 273: 543–545. 10.1038/273543a0 CASPubMedWeb of Science®Google Scholar 23 Fuchs, S. 1979. Immunosuppression of experimental myasthenia gravis. In Plasmapheresis and the Immunobiology of Myasthenia Gravis. P. Dau, Ed. 20–31. Houghton Mifflin, Boston , Massachusetts . Google Scholar 24 Lefvert, A. K. 1981. Anti-idiotypic antibodies against the receptor antibodies in myasthenia gravis. Scand. J. Immunol. 13: 493–497. 10.1111/j.1365-3083.1981.tb00161.x PubMedWeb of Science®Google Scholar 25 Sege, K. & P. A. Petterson. 1978. Use of anti-idiotypic antibodies as cell surface receptor probes. Immunol. 75: 2443–2447. CASPubMedWeb of Science®Google Scholar 26 Namba, T., S. B. Brown & D. Grob. 1970. Neonatal myasthenia gravis: report of two cases and review of the literature. Pediatrics 45: 488–504. 10.1542/peds.45.3.488 CASPubMedWeb of Science®Google Scholar 27 Lefvert, A. K., P. O. Osterman, G. Matell & R. Pirskanen. 1980. Ace-tylcholine receptor antibodies in children to myasthenic mothers. Manuscript. Google Scholar 28 Keesey, J., J. Lindstrom, H. Cokely & C. Herrman. 1977. Anti-acetylcholine receptor antibody in neonatal myasthenia gravis. N. Engl. J. Med. 296: 55. 10.1056/NEJM197701062960124 CASPubMedWeb of Science®Google Scholar Citing Literature Volume377, Issue1Myasthenia Gravis: Pathophysiology and ManagementDecember 1981Pages 125-142 ReferencesRelatedInformation
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