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Potential therapeutic failure of generic vancomycin in a liver transplant patient with MRSA peritonitis and bacteremia

2009; Elsevier BV; Volume: 59; Issue: 4 Linguagem: Inglês

10.1016/j.jinf.2009.08.005

1532-2742

Carlos A. Rodríguez, María Agudelo, Juan Carlos Cataño, Andrés F. Zuluaga, Ómar Vesga,

Pharmaceutical studies and practices

We report a case of generic vancomycin treatment failure in a liver transplant patient with MRSA peritonitis and bacteremia, followed by a rapid sterilization of blood and peritoneal fluid after switching to the branded product. It raises concern about therapeutic equivalence of generic vancomycin.