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The detection of antibodies in human and animal filariases by counterimmunioelectrophoresis with Dirofilaria immitis antigens

1976; Cambridge University Press; Volume: 50; Issue: 1 Linguagem: Inglês

10.1017/s0022149x00028856

1475-2697

Robert S. Desowitz, Steven R. Una,

Trypanosoma species research and implications

Counterimmunoelectrophoresis revealed the presence of precipitin antibody in all of 6 dogs and the 1 cat infected with Dirofilaria immitis and in the serum of 17 of 24 individuals living in a setting of hyperendemic subperiodic bancroftian filariasis. Antigens used in the test were prepared from microfilariae and adult male D. immitis. Some humans and animals had antibodies to both antigens while others had antibodies against microfilariae or adult worms only. The presence of soluble circulating antigen was detected in the sera of two dogs with high microfilaraemias.