Produção Nacional
Extranodal follicular dendritic cell sarcoma of the palate
1999; Elsevier BV; Volume: 87; Issue: 2 Linguagem: Inglês
10.1016/s1079-2104(99)70274-x
ISSN1528-395X
AutoresVera Cavalcanti de Araújo, Marília Trierveiler Martins, Fued Samir Salmen, Ney Soares de Araújo,
Tópico(s)Tumors and Oncological Cases
ResumoAbstract Follicular dendritic cell tumors are uncommon and usually occur in lymph nodes. We report thecase of a follicular dendritic cell tumor that occurred in the palate of a 14-year-old boy andmanifested itself as a nodular mass. Histologically, the neoplasm consisted of spindle-shaped oroval-shaped cells with eosinophilic cytoplasms and nuclei with delicate, dispersed chromatin. Thelesional cells were principally arranged in diffuse, fascicular patterns with vaguely whorled orstoriform areas. Focal multinucleate tumor giant cells and lymphocytes were observed throughoutthe neoplasm. Immunohistochemically, tumor cells were positive for the follicular dendritic cellmarkers CD21, CD35, and CD23 and for S-100 protein, CD68, and muscle-specific actin. Tumorcells were negative for LCA, CD20, EMA, CK (AE1/AE3), HMB45, and CD34. Lymphocytes werepositive for LCA and CD45RO. Although follicular dendritic cell sarcoma is a very uncommon tumor,it should be included in the differential diagnosis of tumors in this location.(Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999;87:209-14)
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