Artigo Revisado por pares

Insulin resistance and lipid metabolism

1993; Lippincott Williams & Wilkins; Volume: 4; Issue: 3 Linguagem: Inglês

10.1097/00041433-199306000-00004

ISSN

1473-6535

Autores

Keith N. Frayn,

Tópico(s)

Lipoproteins and Cardiovascular Health

Resumo

Insulin resistance is characterized by alterations of lipid metabolism, particularly elevated plasma triacylglycerol and decreased HDL-cholesterol concentrations and the presence of small, dense LDL particles. These observations are difficult to interpret in terms of cause and effect. In this review, the hypothesis is put forward that these changes stem from disruption of the normal precise co-ordination of postprandial lipid metabolism by insulin.

Referência(s)
Altmetric
PlumX