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Role of the carboxyl‐terminal region of the PVP protein (F 0 I subunit) in the H + conduction of F 0 F 1 H + ‐ATP synthase of bovine heart mitochondria

1989; Wiley; Volume: 249; Issue: 1 Linguagem: Inglês

10.1016/0014-5793(89)80016-x

1873-3468

Sergio Papa, F. Guerrieri, Franco Zanotti, J Houštěk, Giuseppe Capozza, Severino Ronchi,

RNA and protein synthesis mechanisms

By means of protein sequencing, labelling with thiol reagents and reconstitution studies it is shown that the carboxyl-terminal region of the PVP protein (F0I subunit, nuclear-encoded protein of Mr 25,000) of mitochondrial F0 promotes transmembrane proton conduction by F0 and the sensitivity of this process to oligomycin.