Meta-Analysis of Quantitative Trait Association and Mapping Studies using Parametric and Non-Parametric Models
2013; OMICS Publishing Group; Linguagem: Inglês
10.4172/2155-6180.s1-001
ISSN2155-6180
Autores Tópico(s)Genetics and Plant Breeding
ResumoIn this paper, we discuss several parametric methods applicable to meta-analysis of quantitative trait association and mapping studies, and propose the use of a non-parametric Bayesian model with a Dirichlet process prior (referred to as the DPP model) for QTL meta-analysis.The DPP model relaxes the normality assumption of study-specific
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