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Queyrat's erythroplasia of the penis treated by beta particle irradiation

1969; Wiley; Volume: 42; Issue: 503 Linguagem: Inglês

10.1259/0007-1285-42-503-855

1748-880X

B.S. Mantell, W. Y. Morgan,

Urologic and reproductive health conditions

This article describes the construction and use of an yttrium 90 applicator in the treatment of a patient with Queyrat's erythroplasia, or Bowen's disease, of the glans penis (Blau and Hyman, 1955). H.B., aged 66, was admitted to The London Hospital in May 1966 complaining of a red area on the glans penis for about four months. There was no pain or irritation; he had been circumcised in childhood. A biopsy was taken from the region of the corona and this was reported as follows: “Inflamed area of irregular epithelial overgrowth rather nearer Erythroplasia of Queyrat than Balanitis Circumscripta of Zoon. The inflammation on the deep surface appears to be related to surface polymorph infiltration and is absent locally. Abnormal epithelial cells are not frequent, although there are many mitoses.” The patient was referred to the radiotherapy department on 2.6.66. On examination there was a scaly red non-indurated plaque 4 × 3 cm on the dorsum of the glans penis extending from the urethral meatus to the post-coronal sulcus (Fig. 1). The meatus measured only about 3 mm. There were soft non-significant lymph nodes palpable in the right groin. It was decided to treat the lesion with β-particle irradiation. An accurately fitting cast of the area to be treated was made in silicone rubber impregnated with yttrium oxide as described below. The area covered included the whole glans and the distal end of the shaft, allowing a margin of 1·5 cm beyond the limit of the visible lesion.