Alkaloids and other compounds from seeds of Tabernaemontana cymosa
1997; Elsevier BV; Volume: 45; Issue: 2 Linguagem: Inglês
10.1016/s0031-9422(96)00645-0
ISSN1873-3700
AutoresHans Achenbach, Monika Benirschke, Rubén Torrenegra,
Tópico(s)Natural product bioactivities and synthesis
ResumoFrom the seeds of Tabernaemontana cymosa ( = T. psychotrifolia) 17 indole alkaloids and six lignan glucosides were isolated, besides triacylglycerols, 9,12-octadecadienoic acid, lupeol, (+)-lyoniresinol, obtusifoliol, sweroside and a glucoside of 3-O-methylgallic acid. 9-(β-d-Glucopyranosyloxy)-tetrahydroalstonine, (+)-5,5′-dimethoxy-9-O-(β-d-glucopyranosyl)lariciresinol, (−)-2α-O-(β-d-glucopyranosyl)-lyoniresinol and 3-O-(β-d-glucopyranosyl)-5-O-methylgallic acid are described for the first time. Structural determination is based on spectroscopic studies and/or on comparison with authentic compounds. Some of the isolated substances exhibited significant antifungal and/or cytotoxic effects.
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