Cannabisativine, a new alkaloid from cannabis sativa l. root
1975; Elsevier BV; Volume: 16; Issue: 33 Linguagem: Inglês
10.1016/s0040-4039(00)75003-9
ISSN1873-3581
AutoresHermann L. Latter, Donald J. Abraham, Carlton E. Turner, Joseph E. Knapp, Paul L. Schiff, David J. Slatkin,
Tópico(s)Biochemical Analysis and Sensing Techniques
ResumoThe roots of Cannabis sativa have medicinal potential evidenced in the ethnopharmacological data. However, few studies describe its chemical and pharmacological profile, what justify the interest in its study. This chapter emphasizes the use of C. sativa roots cultivated in the Vale do São Francisco region, Brazilian northeastern region, presenting promising results attributed to its aqueous extract. The chemical profile was obtained by analytical techniques, allowing the identification of compounds previously described in the roots. The pharmacological study presented the anti-inflammatory, antinociceptive, anti-dysmenorrheic, and anti-asthmatic effects, causing no harm to the central nervous system or toxic effects. These results were reported for the first time for the roots of the plants cultivated in the Vale do São Francisco region, representing a progress in the knowledge of its chemicals and pharmacological aspects, proving the ethnopharmacological indications and expanding the horizons of therapeutic possibilities of Cannabis.
Referência(s)