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Prevalence of Acne Vulgaris in Patients with Down Syndrome

2010; Karger Publishers; Volume: 220; Issue: 4 Linguagem: Inglês

10.1159/000284680

1421-9832

Ediléia Bagatin, Cristhine Souza Leão Kamamoto, Lilia Ramos dos Santos Guadanhim, Adriana Sañudo, Marilia Costa Dias, Isa Mara Barraviera, Fernanda Marciano Consolim‐Colombo,

Skin Protection and Aging

<i>Background/Objective:</i> Acne vulgaris exhibits a worldwide prevalence of up to 95% among adolescents. On the other hand, Down syndrome is an autosomal chromosomal disorder with associated dermatoses and a tendency to obesity. There are no data on its association with acne. Our aim was to detect the prevalence of acne, its forms and associated factors in Down syndrome. <i>Method:</i> A cross-sectional study including 89 subjects aged 10–28 years from Associação de Pais e Amigos dos Excepcionais-São Paulo to verify acne, metabolic and hormonal disorders by interview, clinical and laboratory examinations. <i>Results:</i> We evaluated 49 (55%) males and 40 (45%) females. A weak agreement between self-estimation for acne and examination result was detected. The overall prevalence of acne was 70.8%: 83.7% in males and 55% in females. The prevalence of acne in the age groups 10–17 and 18–28 was 62 and 78.7%, respectively. Facial comedonal acne was mostly detected. The prevalence of obesity was 40%, that of metabolic disorders 7% and that of hyperandrogenism (in females) 15%. Except for gender, no other factor evaluated correlated with acne. <i>Conclusion:</i> A low prevalence of acne in Down syndrome, a predominance in males aged 18–28 and a facial comedonal form were detected. An association with obesity, metabolic disorders or hyperandrogenemia was not assessed.