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The relation of “Silent” T wave inversion to cardiovascular disease in an epidemiologic study

1970; Elsevier BV; Volume: 25; Issue: 3 Linguagem: Inglês

10.1016/s0002-9149(70)80010-8

1879-1913

Leon D. Ostrander,

Cardiac electrophysiology and arrhythmias

Forty-seven adults (24 men and 23 women), approximately 1 percent of the examined population of Tecumseh, Mich. had nonspecific T wave inversion unassociated with symptoms or physical signs of heart disease or administration of drugs. They had a higher age-specific prevalence of obesity, hypertension, hypercholesterolemia and hyperglycemia than the total examined Tecumseh population. Individuals with silent T wave inversion also had a significantly higher mortality than expected for a representative sample of Tecumseh participants of similar age and sex. The physiologic abnormalities and course of these 47 persons suggests that even without other symptoms or signs T wave inversions is usually an indication of hypertensive or coronary heart disease. T wave inversion may be a benign finding in the occasional individual who remains free of overt disease and has no abnormalities predisposing to heart disease. Forty-seven adults (24 men and 23 women), approximately 1 percent of the examined population of Tecumseh, Mich. had nonspecific T wave inversion unassociated with symptoms or physical signs of heart disease or administration of drugs. They had a higher age-specific prevalence of obesity, hypertension, hypercholesterolemia and hyperglycemia than the total examined Tecumseh population. Individuals with silent T wave inversion also had a significantly higher mortality than expected for a representative sample of Tecumseh participants of similar age and sex. The physiologic abnormalities and course of these 47 persons suggests that even without other symptoms or signs T wave inversions is usually an indication of hypertensive or coronary heart disease. T wave inversion may be a benign finding in the occasional individual who remains free of overt disease and has no abnormalities predisposing to heart disease.