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Heligmosomoides polygyrus: A model for chronic gastrointestinal helminthiasis

1992; Elsevier BV; Volume: 8; Issue: 2 Linguagem: Inglês

10.1016/0169-4758(92)90084-f

1873-1473

Fernando Monroy, F J Enriquez,

Parasites and Host Interactions

Establishment of chronic infections and strain-dependent variation in resistance to challenge infections are well-known features of the relationship between mice and the intestinal nematode parasite Heligmosomoides polygyrus. Here, Fernando Monroy and Javier Enriquez examine host responses, immunogenic and nonimmunogenic antigens of the parasite, and parasite immune evasion strategies in this useful laboratory mouse model of nematode parasitism of mammals.