Portal de Periódicos da CAPES

Sitagliptin Manufacture: A Compelling Tale of Green Chemistry, Process Intensification, and Industrial Asymmetric Catalysis

2011; Wiley; Volume: 50; Issue: 9 Linguagem: Inglês

10.1002/anie.201007051

1521-3773

Aman A. Desai,

Innovative Microfluidic and Catalytic Techniques Innovation

Generation gap: Three generations of process research and development towards the industrial manufacture of sitagliptin phosphate (1), a leading drug for type 2 diabetes, are highlighted.