Distinct B Cell Subpopulations Differ in Their Genetic Requirements for Activation by T Helper Cells
1982; Wiley; Volume: 64; Issue: 1 Linguagem: Inglês
10.1111/j.1600-065x.1982.tb00422.x
ISSN1600-065X
AutoresAlfred Singer, Yoshihiro Asano, Minoru Shigeta, Karen S. Hathcock, Aftab Ahmed, C. Garrison Fathman, Richard J. Hodes,
Tópico(s)CAR-T cell therapy research
ResumoImmunological ReviewsVolume 64, Issue 1 p. 137-160 Distinct B Cell Subpopulations Differ in Their Genetic Requirements for Activation by T Helper Cells Alfred Singer, Alfred Singer Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorYoshihiro Asano, Yoshihiro Asano Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorMinoru Shigeta, Minoru Shigeta Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorKaren S. Hathcock, Karen S. Hathcock Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorAftab Ahmed, Aftab Ahmed Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorC. Garrison Fathman, C. Garrison Fathman Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorRichard J. Hodes, Richard J. Hodes Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this author Alfred Singer, Alfred Singer Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorYoshihiro Asano, Yoshihiro Asano Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorMinoru Shigeta, Minoru Shigeta Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorKaren S. Hathcock, Karen S. Hathcock Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorAftab Ahmed, Aftab Ahmed Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorC. Garrison Fathman, C. Garrison Fathman Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this authorRichard J. Hodes, Richard J. Hodes Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, 20205; and Division of Immunology, Department of Medicine, Stanford University School of Medicine, Stanford CA., U.S.A.Search for more papers by this author First published: June 1982 https://doi.org/10.1111/j.1600-065X.1982.tb00422.xCitations: 45AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Ahmed, A. & Scher, I. (1979) Murine B cell heterogeneity defined by anti-Lyb5, an allo-antiserum specific for a late-appearing B lymphocyte subpopulation. In B lymphocytes in the Immune Response, eds. M. Cooper, D. E. Mosier, E. S. Vitetta & I. Scher p. 117, Elsevier-North Holland, Inc. New York . Ahmed, A., Scher, I., Sharrow, S. C. Smith, A. H., Paul, W. E., Sachs, D. H. & Sell, K. W. (1977) B lymphocyte heterogeneity: development of an alloantiserum which distinguishes B lymphocyte differentiation alloantigens. J. exp. Med. 145, 101. Asano, Y., Singer, A. & Hodes, R. J. (1981) Role of the major histocompatibility complex in T cell activation of B cell subpopulations. MHC restricted and unrestricted B cell responses are mediated by distinct B cell subpopulations. J. exp. Med. 154, 1100. Bevan, M. J. (1977) In a radiation chimera host H-2 antigens determine the immune responsiveness of donor cytotoxic cells. Nature (Lond.) 269, 417. Boswell, H. S., Ahmed, A., Scher, I. & Singer, A. (1980a) Role of accessory cells in B cell activation. II. The interaction of B cells with accessory cells results in the exclusive activation of an Lyb5+ B cell subpopulation. J. Immunol. 125, 1340. Boswell, H. S., Nerenberg, M. I., Scher, I. & Singer, A. (1980b) Role of accessory cells in B cell activation. III. Cellular analysis of primary immune response deficits in CBA/N mice: presence of an accessory cell-B cell interaction defect. J. exp. Med. 152, 1194. Erb, P., Meier, B., Marasunage, T. & Feldmann, M. (1979) Nature of T-cell macrophage interaction in helper-cell induction in vitro. IL Two stages of T-helper-cell differentiation analyzed in irradiation and allophenic chimeras. J. exp. Med. 149, 686. Hodes, R. J., Asano, Y., Shigeta, M., Hathcock, K. S., Kimoto, M., Fathman, C. G. & Singer, A. (1981) A single monoclonal T helper cell population can activate different B cell subpopulations via distinct activation pathways. In Isolation, Characterization and Utilization of T Lymphocyte Clones, eds. C. G. Fathman & F. Fitch (in press). Hodes, R. J., Hathcock, K. S. & Singer, A. (1979) Cellular and genetic control of antibody responses. VI. Expression of Ir gene function by H-2a accessory cells, but not H-2a T or B cells in responses to TNP-(T, G)-A-L. J. Immunol. 123, 2823. Janeway, C. A., Murgita, R. A., Weinbaum, F. L, Asofsky, R. & Wigzell, H. (1977) Evidence for an immunoglobulin-dependent antigen-specific helper T cell. Proc. natl. Acad Sci. USA 74, 4582. Kappler, J. W. & Marrack, P. (1978) The role of H-2 linked genes in helper T cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression. J. exp. Med. 148, 1510. Katz, D. H., Hamaoka, T. & Benacerraf, B. (1973) Cell interactions between histoincompatible T and B lymphocytes. II. Failure of physiologic cooperative interactions between T and B lymphocytes from allogeneic donor strains in humoral response to hapten-protein conjugates. J. exp. Med. 137, 1405. Katz, D. H., Skidmore, B. J., Katz, L. R. & Bogowitz, C. A. (1978) Adaptive differentiation of murine lymphocytes. I. Both T and B lymphocytes differentiating in F1—parental chimeras manifest preferential cooperative activity for partner lymphocytes derived from the same parental type corresponding to the chimeric host. J. exp. Med. 148, 727. Marrack, P., Harwell, L., Kappler, J., Kawahara, D., Keller, D. & Swierkosz, J. (1979) Helper T cell interactions with B cells and macrophages. In Immunologic Tolerance and Macrophage Function, eds. P. Baram, J. Battisto & C. W. Pierce, p. 31. Elsevier-North Holland Inc., New York . McDougal, J. S. & Cort, S. P. (1978) Generation of T helper cells in vitro. IV. F1 T helper cells primed with antigen-pulsed parental macrophages are genetically restricted in their antigen-specific activity. J. Immunol. 120, 445. Mond, J. J., Scher, I., Mosier, D. E., Blaese, M. & Paul, W. E. (1978) T-independent responses in B cell defective CBA/N mice to Brucella abortus and to trinitrophenyl (TNP) conjugates of Brucella abortus. Eur. J. Immunol. 8, 459. Mosier, D. E., Zitron, I. M., Mond, J. J., Ahmed, A., Scher, I. & Paul, W. E. (1977) Surface immunoglobulin D as a functional receptor for a subclass of B lymphocytes. Immunol Rev. 37, 89. Rosenthal, A. S. & Shevach, E. M. (1973) Function of macrophages in antigen recognition by guinea pig T lymphocytes. J. exp. Med. 138, 1194. Shigetta, M. & Fathman, C. G. (1981) I region genetic restrictions imposed upon the recognition of KLH by murine T cell clones. Immunogenetics (In press). Shih, W. H., Matzinger, P. C, Swain, S. L. & Dutton, R. W. (1980) Analysis of histocompatibility requirements for proliferative and helper T cell activity. T cell populations depleted of alloreactive cells by negative selection. J. exp. Med. 152, 1311. Singer, A., Cowing, C, Hathcock, K. S., Dickler, H. B. & Hodes, R. J. (1978) Cellular and genetic control of antibody responses in vitro. III. Immunie response gene regulation of accessory cell function. J. exp. Med. 147, 1611. Singer, A., Dickler, H. B. & Hodes, R. J. (1977) Cellular and genetic control of antibody responses in vitro. II. Ir gene control of primary IgM responses to trinitrophenyl conjugates of (T, G)-A-L and (H, G)-A-L. J. exp. Med 146, 1096. Singer, A., Hathcock, K. S. & Hodes, R. J. (1979) Cellular and genetic control of antibody responses. V. Helper T-cell recognition of H-2 determinants on accessory cells but not B cells. J. exp. Med 149, 1208. Singer, A., Hathcock, K. S. & Hodes, R. J. (1980) Cellular and genetic control of antibody responses. VIII. MHC restricted recognition of accessory cells, but not B cells, by parent-specific subpopulations of normal F1 T helper cells. J. Immunol. 124, 1311. Singer, A., Hathcock, K. S. & Hodes, R. J. (1981a) Self recognition in allogeneic radiation bone marrow chimeras. A radiation-resistant host element dictates the self specificity and immune response gene phenotype of T-helper cells. J. exp. Med. 153, 1286. Singer, A., Morrissey, P. J., Hathcock, K. S., Ahmed, A., Scher, I. & Hodes, R. J. (1981b) Role of the major histocompatibility complex in T cell activation of B cell subpopulations. Lyb5+ and Lyb5− B cell subpopulations differ in their requirement for major histocompatibility complex-restricted T cell recognition. J. exp. Med. 154, 501. Sprent, J. (1978a) Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. I. Failure to collaborate with B cells of the opposite strain not associated with active suppression. J. exp. Med. 147, 1142. Sprent, J. (1978b) Restricted helper function of F1 hybrid T cells positively selected to heterologous erythrocytes in irradiated parental strain mice. IL Evidence for restrictions affecting helper cell induction and T-B collaboration, both mapping to the K-end of the H-2 complex. J. exp. Med. 147, 1159. Sprent, J. (1978c) Restricted helper function of F1—parent bone marrow chimeras controlled by K-end of H-2 complex. J. exp. Med 147, 1838. Swierkosz, J., Rock, K., Marrack, P. & Kappler, J. W. (1978) The role of H-2 linked genes in helper T cell function. II. Isolation on antigen-pulsed macrophages of two separate populations of F1 helper cells each specific for antigen and one set of parental H-2 products. J. exp. Med. 147, 554. Yamashita, U. & Shevach, E. M. (1978) The histocompatibility restrictions on macrophage T-helper cell interaction determine the histocompatibility restrictions on T-helper cell B-cell interaction. J. exp. Med. 148, 1171. Zinkernagel, R. M., Callahan, G. N., Althage, A. Cooper, Klein, P. A. & Klein, J. (1978) On the thymus in the differentiation of “H-2 self-recognition” by T cells: evidence for dual recognition J. exp. Med. 147, 882. Citing Literature Volume64, Issue1June 1982Pages 137-160 ReferencesRelatedInformation
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