T‐cell‐derived malignant lymphoma in the boxer breed
2004; Wiley; Volume: 2; Issue: 3 Linguagem: Inglês
10.1111/j.1476-5810.2004.00047.x
ISSN1476-5829
AutoresDavid M. Lurie, Michael D. Lucroy, S. Griffey, Eric Simonson, Bruce R. Madewell,
Tópico(s)Immunotherapy and Immune Responses
ResumoAbstract The boxer breed of dog is at high risk for a variety of neoplasms including lymphoma. In this observational study, tissue sections from boxer dogs with lymphoma were immunostained for T and B lymphocyte distinction, and the results compared with similar studies carried out on lymphoma tissues from temporally selected cohorts of golden retriever and rottweiler dogs. The frequency of T‐cell lymphomas was significantly ( P < 0.001 for all comparisons) higher in the boxers than in the rottweilers or golden retrievers. We are unaware of other reports linking immunotype of canine lymphoma with breed; whether other brachycephalic breeds of dogs have a similar preponderance of T‐cell lymphoma awaits further study.
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