Artigo Acesso aberto Revisado por pares

Cyclopentanoid allylsilanes in synthesis: A facile construction of the 5–8 fused carbon framework of asteriscanolide

1998; Elsevier BV; Volume: 39; Issue: 45 Linguagem: Inglês

10.1016/s0040-4039(98)01845-0

ISSN

1873-3581

Autores

Tarun K. Sarkar, Pulak Gangopadhyay, Binay K. Ghorai, Sandip K. Nandy, Jim‐Min Fang,

Tópico(s)

Oxidative Organic Chemistry Reactions

Resumo

A short synthesis of the 5–8 fused carbocyclic system of asteriscanolide, a novel cyclooctane sesquiterpene is described which entails a 5-(3,4) ene cyclization, an allylsilane induced lactone formation and a [3,3] sigmatropic rearrangement in the key steps of the synthesis.

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