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BIBTEX RIS

One-pot three-enzyme synthesis of UDP-GlcNAc derivatives

2011; Royal Society of Chemistry; Volume: 47; Issue: 38 Linguagem: Inglês

10.1039/c1cc14034e

ISSN

1364-548X

Autores

Yi Chen, Vireak Thon, Yanhong Li, Hai Yu, Ding Li, Kam Lau, Jingyao Qu, Liana Hie, Xi Chen,

Tópico(s)

Biochemical and Molecular Research

Resumo

A Pasteurella multocida N-acetylglucosamine 1-phosphate uridylyltransferase (PmGlmU) was cloned and used efficiently with an N-acetylhexosamine 1-kinase (NahK_ATCC55813) and an inorganic pyrophosphatase (PmPpA) for one-pot three-enzyme synthesis of UDP-GlcNAc derivatives with or without further chemical diversification.

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