Produção Nacional
Revisado por pares
Síntese de heterociclos bioativos derivados do ferroceno
2013; Brazilian Chemical Society; Volume: 36; Issue: 1 Linguagem: Inglês
10.1590/s0100-40422013000100024
ISSN1678-7064
AutoresCláudio M. P. Pereira, Dalila Venzke, Gustavo Henrique Goulart Trossini,
Tópico(s)Ferrocene Chemistry and Applications
ResumoSYNTHESIS OF BIOACTIVE HETEROCYCLIC FERROCENE DERIVATIVES.The discovery of ferrocene marked one of the points of departure for modern organometallic chemistry.In general, the compounds of ferrocene derivatives are widely applied in several areas.One of the most important applications of ferrocene is the development of more active drugs, especially in cases where there is resistance to current drugs.Bioactive agents containing ferrocene have proven effective in combating diseases such as cancer, malaria, HIV, Alzheimer and conditions caused by fungi and bacteria.In this context, the present paper aims to highlights the synthesis of heterocycles containing ferrocene moiety and their use in medicinal chemistry.
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