Synthesis and characterization of copper-ibuprofenate complexes with 2, 2′-bipyridine and 1, 10-phenanthrolines and their hydrolytic activities in phosphate diester cleavage
1997; Elsevier BV; Volume: 16; Issue: 4 Linguagem: Inglês
10.1016/0277-5387(96)00214-8
ISSN1873-3719
Autores Tópico(s)Metal-Organic Frameworks: Synthesis and Applications
ResumoAbstract A synthetic investigation of copper (II) ibuprofenate (Ibup) addition compounds with 2, 2′-bipyridine (bpy), 1, 10-phenanthroline (phen) and 2, 9-dimethyl-1, 10-phenanthroline (dmph) has led to the isolation of dinuclear adducts of the forms [Cu(Ibup)2(bpy)]2·4H2O (1) and [Cu(Ibup)2(phen)]2 (2) and a mononuclear adduct Cu(Ibup)2(dmph) (3). Spectroscopic data for adducts 1 and 2 are consistent with a dinuclear structure with two CuN2O2+O chromophors. Each copper is coordinated with two ibuprofenate bridges, a terminal diimine molecule and a monodentate ibuprofenate group complete five-coordination at each metal atom. Spectroscopic data for adduct 3 are consistent with a mononuclear structure having a very distorted square-pyramidal CuN2O2+O chromophore. The CuII atom is coordinated to two nitrogen atoms from a chelating dmph ligand, two car☐ylic oxygens of a bidentate ibuprofenate ion and an oxygen atom of a monodentate car☐ylic group of a second ibuprofenate ion. The reduction of adduct (3) by ascorbic acid produced stable red copper(I) complex of the form [Cu(dmph)2] (Ibup) (4). Spectral data of this adduct indicated that the cation has distorted tetrahedral geometry about the copper atom. The effect of 1 and 2 on the rate of hydrolysis of bis(p-nitrophenyl) phosphate (BNPP) have been examined in aqueous methanol solution at 70°C and pH 7.4.
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