Produção Nacional
Revisado por pares
Amastigotes forms of Trypanosoma cruzi detected in a renal allograft
1997; UNIVERSIDADE DE SÃO PAULO; Volume: 39; Issue: 4 Linguagem: Inglês
10.1590/s0036-46651997000400008
ISSN1678-9946
AutoresMaria Fernanda Carvalho de Camargo, Marcello Fabiano de Franco, Vitor Soares,
Tópico(s)Research on Leishmaniasis Studies
ResumoTrypanosoma cruzi, the causative agent of Chagas’disease assumes two distinct forms in vertebrate hosts: circulating trypomastigote and tissular amastigote. This latter form infects predominantly the myocardium, smooth and skeletal muscle, and central nervous system. The present work describes for the first time the detection of amastigote forms of T. cruzi in the renal parenchyma of a kidney graft recipient one month after transplantation. The patient was serologically negative for Chagas’disease and received no blood transfusion prior to transplant. The cadaver donor was from an endemic area for Chagas’disease. The recipient developed the acute form of the disease with detection of amastigote forms of T. cruzi in the renal allograft biopsy and circulating trypomastigote forms. The present report demonstrates that T. cruzi can infect the renal parenchyma. This mode of transmission warrants in endemic areas of Chagas’disease
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