Revisão Acesso aberto Revisado por pares

Glycogen Turnover Forms Lactate during Exercise

2005; Lippincott Williams & Wilkins; Volume: 33; Issue: 4 Linguagem: Inglês

10.1097/00003677-200510000-00002

ISSN

1538-3008

Autores

Robert G. Shulman,

Tópico(s)

Adipose Tissue and Metabolism

Resumo

In Brief The power needs of muscle are supplied by rapid anaerobic glycogenolytic ATP generation. Lactate is built up by the mismatch between steady state energy needs and short-term power demands and the increased concentration drives the lactate shuttle. In this model, contributions to fatigue should be looked for in the flux of glucose through glycogen rather than in the concentrations of fuel. The turnover of glycogen in muscle generates lactate and provides ATP rapidly to satisfy the power needs of contraction.

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