Artigo Acesso aberto Revisado por pares

Clinicopathology conferences: Inflammation-induced cholestasis

1998; Lippincott Williams & Wilkins; Volume: 28; Issue: 1 Linguagem: Inglês

10.1002/hep.510280133

ISSN

1527-3350

Autores

James M. Crawford, James L. Boyer,

Tópico(s)

Inflammatory Bowel Disease

Resumo

HepatologyVolume 28, Issue 1 p. 253-260 Clinical ChallengeFree Access Clinicopathology conferences: Inflammation-induced cholestasis James M. Crawford, Corresponding Author James M. Crawford Program in Gastrointestinal Pathology, Yale Liver Center, Yale University School of Medicine, New Haven, CTDepartment of Pathology, Yale University School of Medicine, 310 Cedar Street, P.O. Box 8023, New Haven, CT 06520-8023. Fax: (203) 737-1064===Search for more papers by this authorJames L. Boyer M.D., Ph.D., James L. Boyer M.D., Ph.D. Department of Medicine, Yale Liver Center, Yale University School of Medicine, New Haven, CTSearch for more papers by this author James M. Crawford, Corresponding Author James M. Crawford Program in Gastrointestinal Pathology, Yale Liver Center, Yale University School of Medicine, New Haven, CTDepartment of Pathology, Yale University School of Medicine, 310 Cedar Street, P.O. Box 8023, New Haven, CT 06520-8023. Fax: (203) 737-1064===Search for more papers by this authorJames L. Boyer M.D., Ph.D., James L. Boyer M.D., Ph.D. Department of Medicine, Yale Liver Center, Yale University School of Medicine, New Haven, CTSearch for more papers by this author First published: 30 December 2003 https://doi.org/10.1002/hep.510280133Citations: 53AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Yamada T, Hoshino M, Hayakawa T, Kamiya Y, Ohhara H, Mizuno K, Yamada H, et al. Bile secretion in rats with indomethacin-induced intestinal inflammation. Am J Physiol Gastrointest Liver Physiol 1996; 270: G804– G812. 2 Arias-Díaz J, Vara E, Gómez M, Moreno A, Torres-Melero J, Balibrea JL. Effect of sepsis-related cytokines on lipid synthesis by isolated human hepatocytes. Eur J Surg 1993; 159: 535– 539.MEDLINE 3 Tilg H, Wilmer A, Vogel W, Herold M, Nolchen B, Judmaier G, Huber C. Serum levels of cytokines in chronic liver diseases. Gastroenterology 1992; 103: 264– 274.MEDLINE 4 Gleeson D, Boyer JL. Intrahepatic cholestasis. In: N McIntyre, J-P Benhamou, J Bircher, M Rizzetto, J Rodes, eds. Oxford Textbook of Clinical Hepatology. Oxford: Oxford Medical Publications, 1991; 1087– 1107. 5 Whiting JF, Green RM, Rosenbluth AB, Gollan JL. Tumor necrosis factor-α decreases hepatocyte bile salt uptake and mediates endotoxin-induced cholestasis. Hepatology 1995; 22: 1273– 1278.MEDLINE 6 Green RM, Whiting JF, Rosenbluth AB, Beier D, Gollan JL. Interleukin-6 inhibits hepatocyte taurocholate uptake and sodium-potassium-adenosinetriphosphatase activity. Am J Physiol Gastrointest Liver Physiol 1994; 267: G1094– G1100. 7 Green RM, Crawford JM. Hepatocellular cholestasis: pathobiology and histological outcome. Semin Liver Dis 1995; 15: 372– 389.MEDLINE 8 Trauner M, Arrese M, Soroka CJ, Ananthanarayanan M, Koeppel TA, Schlosser SF, Suchy FJ, et al. The rat canalicular conjugate export pump (Mrp2) is down-regulated in intrahepatic and obstructive cholestasis. Gastroenterology 1997; 113: 255– 264.MEDLINE 9 Trauner M, Nathanson MH, Rydberg SA, Koeppel TA, Gartung C, Sessa WC, Boyer JL. Endotoxin impairs biliary glutathione and HCO3-excretion and blocks the choleretic effect of nitric oxide in rat liver. Hepatology 1997; 25: 1184– 1191.MEDLINE 10 Bolder U, Tonnu HT, Schteingart CD, Frick E, Hofmann AF. Hepatocyte transport of bile acids and organic anions in endotoxemic rats—impaired uptake and secretion. Gastroenterology 1997; 112: 214– 225.MEDLINE 11 Moseley RH. Sepsis-associated cholestasis. Gastroenterology 1997; 112: 302– 306.MEDLINE 12 Shiomi M, Wakabayashi Y, Sano T, Shinoda Y, Nimura Y, Ishimura Y, Suematsu M. Nitric oxide suppression reversibly attenuates mitochondrial dysfunction and cholestasis in endotoxemic rat liver. Hepatology 1998; 27: 108– 115.MEDLINE 13 Zuck TF, Bensinger TA, Peck CC, Chillar RK, Beutler E, Button LN, McCurdy PR, et al. The in vivo survival of red blood cells stored in modified CDP with adenine: report of a multi-institutional cooperative effort. Transfusion 1977; 17: 374– 382.MEDLINE 14 Watkins JB. Neonatal cholestasis: developmental aspects and current concepts. Semin Liver Dis 1993; 13: 276– 288.MEDLINE 15 Lefkowitch JH. Bile ductular cholestasis: an ominous histopathologic sign related to sepsis and "cholangitis lenta." Hum Pathol 1982; 13: 19– 24.MEDLINE 16 Farrell GC. Drug-induced cholestasis. In: GC Farrell, ed. Drug-Induced Liver Disease. Edinburgh: Churchill Livingstone. 1994; 319– 370. 17 Wiechmann DA, Heubi JH. Pediatric hepatobiliary disease. Curr Opin Gastroenterol 1997; 13: 427– 431. 18 Sokol RJ, Taylor SF, Devereaux MW, Khandwala R, Sondheimer NJ, Shikes RH, Mierau G. Hepatic oxidant injury and glutathione depletion during total parenteral nutrition in weanling rats. Am J Physiol Gastrointest Liver Physiol 1996; 270: G691– G700. 19 Farrell MK, Bucuvalas JC. Systemic disease and the liver. In: FJ Suchy, ed. Liver Disease in Children. St. Louis: Mosby. 1994; 580– 604. 20 Quigley EMM, Marsh MN, Shaffer JL, Markin RS. Hepatobiliary complications of total parenteral nutrition. Gastroenterology 1993; 104: 286– 301.MEDLINE 21 Bhatia J, Moslen MT, Haque AK, McCleery R, Rassin DK. Total parenteral nutrition-associated alterations in hepatobiliary function and histology in rats: is light exposure a clue? Pediatr Res 1993; 33: 487– 492.MEDLINE 22 Grinko I, Geerts A, Wisse E. Experimental biliary fibrosis correlates with increased numbers of fat-storing and Kupffer cells, and portal endotoxemia. J Hepatol 1995; 23: 449– 458.MEDLINE 23 Shindo M, Mullin GE, Braun-Elwert L, Bergasa NV, Jones EA, James SP. Cytokine mRNA expression in the liver of patients with primary biliary cirrhosis (PBC) and chronic hepatitis B (CHB). Clin Exp Immunol 1996; 105: 254– 259.MEDLINE 24 Crawford JM. Cellular and molecular biology of the inflamed liver. Curr Opin Gastroenterol 1997; 13: 175– 185. 25 Uhl B, Speth V, Wolf B, Jung G, Bessler WG, Hauschildt S. Rapid alterations in the plasma membrane structure of macrophages stimulated with bacterial lipopeptides. Eur J Cell Biol 1992; 58: 90– 98.MEDLINE 26 Spitzer JA, Zhang P. Hepatic cellular interactions in endotoxaemia and sepsis. Biochem Soc Trans 1995; 23: 993– 998.MEDLINE 27 Roelofsen H, Schoemaker B, Bakker C, Ottenhoff R, Jansen PLM, Elferink RPJO. Impaired hepatocanalicular organic anion transport in endotoxemic rats. Am J Physiol Gastrointest Liver Physiol 1995; 269: G427– G434. 28 Moseley RH, Wang W, Takeda H, Lown K, Shick L, Ananthanarayanan M, Suchy FJ. Effect of endotoxin on bile acid transport in rat liver—a potential model for sepsis-associated cholestasis. Am J Physiol 1996; 271: G137– G146.MEDLINE 29 Perrault J, McGill DB, Ott BJ, Taylor WF. Liver biopsy: complications in 1000 inpatients and outpatients. Gastroenterology 1978; 74: 103– 106.MEDLINE 30 Garcia-Tsao G, Boyer JL. Outpatient liver biopsy: how safe is it. Ann Intern Med 1993; 118: 150– 153.MEDLINE 31 Tobkes AI, Nord HJ. Liver biopsy: review of methodology and complications. Dig Dis 1995; 13: 267– 274.MEDLINE 32 Froehlich F, Lamy O, Fried M, Gonvers JJ. Practice and complications of liver biopsy: results of a nationwide survey in Switzerland. Dig Dis Sci 1993; 38: 1480– 1484.MEDLINE 33 McAfee JH, Keffe EB, Lee RG, Rösch J. Transjugular liver biopsy. Hepatology 1992; 15: 726– 732.MEDLINE 34 Sawyer AM, McCormick PA, Tennyson GS, Chin J, Dick R, Scheuer PJ, Burroughs AK, et al. A comparison of transjugular and plugged-percutaneous liver biopsy in patients with impaired coagulation. J Hepatol 1993; 17: 81– 85.MEDLINE 35 Desmet VJ. Cholestasis: extrahepatic obstruction and secondary biliary cirrhosis. In: RNM MacSween, PP Anthony, PJ Scheuer, AD Burt, BC Portmann, eds. Pathology of the Liver. Edinburgh: Churchill Livingstone. 1994; 425– 476. 36 Van Ness MM, Diehl AM. Is liver biopsy useful in the evaluation of patients with chronically elevated liver enzymes. Ann Intern Med 1989; 111: 473– 478.MEDLINE 37 Jenkins D, Gilmore IT, Doel C, Gallivan S. Liver biopsy in the diagnosis of malignancy. Q J Med 1995; 88: 819– 825. 38 Sweet RD. An acute febrile neutrophilic dermatosis. Br J Dermatol 1964; 76: 349– 356. 39 Cohen PR, Talpaz M, Kurzrock R. Malignancy-associated Sweet's syndrome: review of the world literature. J Clin Oncol 1988; 6: 1887– 1897.MEDLINE 40 Reuss-Borst MA, Pawelec G, Saal JG, Horny HP, Muller CA, Waller HD. Sweet's syndrome associated with myelodysplasia: possible role of cytokines in the pathogenesis of the disease. Br J Haematol 1993; 84: 356– 358.MEDLINE 41 Park JW, Mehrotra B, Barnett BO, Baron AD, Venook AP. The Sweet syndrome during therapy with granulocyte colon-stimulating factor. Ann Intern Med 1992; 116: 996– 998.MEDLINE 42 Paydas S, Sahin B, Seyrek E, Soylu M, Gonsulsen G, Acar A, Tuncer I. Sweet's syndrome associated with G-CSF. Br J Haematol 1993; 85: 191– 192.MEDLINE 43 Terada M, Mizuno Y, Ryourin H, Kumagai M, Ikeda T, Nakanuma Y. A case of Sweet's syndrome with intrahepatic cholestasis. Nippon Shokakibyo Gakkai Zasshi 1992; 89: 2629– 2633.MEDLINE 44 Akovbyan V, Talanin N, Tukhvatullina Z. Sweet's syndrome in patients with kidney and liver disorders. Cutis 1992; 49: 448– 450.MEDLINE 45 Krolikowski FJ, Reuter K, Shultis EW. Acute febrile neutrophilic dermatosis (Sweet's syndrome) associated with lymphoma. Hum Pathol 1985; 16: 520– 522.MEDLINE 46 Matta M, Malak J, Tabet E. Sweet's syndrome: systemic associations. Cutis 1973; 12: 561– 565. 47 Ishak KG, Rogers WA. Cryptogenic acute cholangitis—association with toxic shock syndrome. Am J Clin Pathol 1981; 76: 619– 626.MEDLINE 48 Hoogendoorn M, Van Krieken JHJM, Bieger R. A 37-year-old man with cholestatic jaundice and a prior history of Hodgkin's disease. Ann Hematol 1995; 70: 325– 328.MEDLINE 49 Dich NH, Goodman ZD, Klein MA. Hepatic involvement in Hodgkin's disease: clues to histologic diagnosis. Cancer 1989; 64: 2121– 2126.MEDLINE 50 Crawford JM. Graft-versus-host disease of the liver. In: JLM Ferrara, J Deeg, S Burakoff, eds. Graft-Versus-Host Disease. New York: Dekker. 1996; 315– 336. 51 Becker SD, LaMont JT. Postoperative jaundice. Semin Liver Dis 1988; 8: 183– 190.MEDLINE 52 Nolan JP. Intestinal endotoxins as mediators of hepatic injury—an idea whose time has come again. Hepatology 1989; 10: 887– 891.MEDLINE 53 Bird GLA, Sheron N, Goka AKL, Alexander GL, Williams RS. Increased plasma tumor necrosis factor in severe alcoholic hepatitis. Ann Intern Med 1990; 112: 917– 920.MEDLINE 54 Holman JM, Saba TM. Hepatocyte injury during post-operative sepsis: activated neutrophils as potential mediators. J Leukoc Biol 1988; 43: 193– 203.MEDLINE 55 Latham PS, Menkes E, Philips MJ, Jeejeebhoy KN. Hyperalimentation-associated jaundice: an example of a serum factor inducing cholestasis in rats. Am J Clin Nutr 1985; 41: 61– 65.MEDLINE 56 Tiggelman AMB, Boers W, Lintherst C, Brand HS, Sala M, Chamuleau RAF. Interleukin-6 production by human liver (myo)fibroblasts in culture. Evidence for a regulatory role of LPS, IL-1β and TNFα. J Hepatol 1995; 23: 295– 306.MEDLINE 57 Swain MG, Tjandra K, Kanwar S, Kubes P. Neutrophil adhesion is impaired in a rat model of cholestasis. Gastroenterology 1995; 109: 923– 932.MEDLINE 58 Ayres RCS, Neuberger JM, Shaw J, Joplin R, Adams DH. Intercellular adhesion molecule-1 and MHC antigens on human intrahepatic bile duct cells: effect of pro-inflammatory cytokines. Gut 1993; 34: 1245– 1249.MEDLINE 59 Czaja AJ. Chronic graft-versus-host disease and primary biliary cirrhosis: sorting the puzzle pieces. Lab Invest 1994; 70: 589– 592.MEDLINE 60 Paradis K, Le ONL, Russo P, St-Cyr M, Fournier H, Bu DW. Characterization and response to interleukin 1 and tumor necrosis factor of immortalized murine biliary epithelial cells. Gastroenterology 1995; 109: 1308– 1315.MEDLINE 61 Matsumoto K, Fujii H, Michalopoulos G, Fung JJ, Demetris AJ. Human biliary epithelial cells secrete and respond to cytokines and hepatocyte growth factors in vitro: interleukin-6, hepatocyte growth factor and epidermal growth factor promote DNA synthesis in vitro. Hepatology 1994; 20: 376– 382.MEDLINE 62 Fox ES, Thomas P, Broitman SA. Hepatic mechanisms for clearance and detoxification of bacterial endotoxins. J Nutr Biochem 1990; 1: 620– 628. 63 Spitzer JA, Mayer AMS. Hepatic neutrophil influx: eicosanoid and superoxide formation in endotoxemia. J Surg Res 1993; 55: 60– 67.MEDLINE 64 Balis JU, Rappaport ES, Gerber L, Fareed J, Buddingh F, Messmore HL. A primate model for prolonged endotoxin shock. Blood-vascular reactions and effects of glucocorticoid treatment. Lab Invest 1978; 38: 511– 523.MEDLINE 65 Panes J, Perry MA, Anderson DC, Muzykantov VR, Carden DL, Miyasaka M, Granger DN. Portal hypertension enhances endotoxin-induced intercellular adhesion molecule 1 up-regulation in the rat. Gastroenterology 1996; 110: 866– 874.MEDLINE 66 Jaeschke H, Essani NA, Fisher MA, Vonderfecht SL, Farhood A, Smith CW. Release of soluble intercellular adhesion molecule 1 into bile and serum in murine endotoxin shock. Hepatology 1996; 23: 530– 536.MEDLINE 67 Van Oosten N, Van de Bilt E, De Vries HE, Van Berkel TJC, Kuiper J. Vascular adhesion molecule-1 and intercellular adhesion molecule-1 expression on rat liver cells after lipopolysaccharide administration in vivo. Hepatology 1995; 22: 1538– 1546.MEDLINE 68 Kishimoto TK, Rothlein R. Integrins, ICAMs, and selectins: role and regulation of adhesion molecules in neutrophil recruitment to inflammatory sites. Adv Pharmacol 1994; 25: 117– 169.MEDLINE 69 Sakamoto S, Okanoue T, Itoh Y, Sakamoto K, Nishioji K, Nakagawa Y, Yoshida N, et al. Intercellular adhesion molecule-1 and CD18 are involved in neutrophil adhesion and its cytotoxicity to cultured sinusoidal endothelial cells in rats. Hepatology 1997; 26: 658– 663.MEDLINE 70 Spitzer JA, Zhang P, Mayer AMS. Functional characterization of peripheral circulating and liver recruited neutrophils in endotoxic rats. J Leukoc Biol 1994; 56: 166– 173.MEDLINE 71 Callery MP, Mangino MJ, Kamei T, Flye MW. Interleukin-6 production by endotoxin-stimulated Kupffer cells is regulated by prostaglandin E2. J Surg Res 1990; 48: 523– 527.MEDLINE 72 Oka Y, Murata A, Nishijima J, Ogawa M, Mori T. The mechanism of hepatic cellular injury in sepsis: an in vitro study of the implications of cytokines and neutrophils in its pathogenesis. J Surg Res 1993; 55: 1– 8.MEDLINE 73 Moseley RH. Sepsis-associated jaundice. Hepatology 1996; 24: 969– 970.MEDLINE 74 Hoffmann R, Grewe M, Estler H-C, Schulze-Specking A, Decker K. Regulation of tumor necrosis factor-α-mRNA synthesis and distribution of tumor necrosis factor-α-mRNA synthesizing cells in rat liver during experimental endotoxemia. J Hepatol 1994; 20: 122– 128.MEDLINE 75 Handel ML. Transcription factors AP-1 and NF-κB: where steroids meet the gold standard of anti-rheumatic drugs. Inflamm Res 1997; 46: 282– 286.MEDLINE 76 Snover DC. Biopsy Diagnosis of Liver Disease. Baltimore: Williams and Wilkins. 1992; 28. 77 Van de Water J, Gershwin ME. Primary biliary cirrhosis: cells, sera, and soluble factors. Mayo Clin Proc 1993; 68: 1128– 1130.MEDLINE 78 Theise ND, Thung SN, Kumar A, Peralta H, Brody RI, Gallo G, Melamed J, et al. Immunohistochemical characterization of the canals of Hering: evidence of bipotent progenitor cells in the liver. Hepatology 1996; 24: 256A. 79 Crawford AR, Lin X, Crawford JM. The normal adult human liver biopsy: a quantitative reference standard. Hepatology 1998; in press. 80 Baumgartner U, Schölmerich J, Karsch J, Gerok W, Farthmann EH. Loss of zonal heterogeneity and cell polarity in rat liver with respect to bile acid secretion after bile drainage. Gastroenterology 1991; 100: 1054– 1061.MEDLINE 81 Monte MJ, Badia MD, Palomero F, El-Mir MY, Alonso JR, Marin JJG. Effects of selective zonal injury on bile acid-induced bile flow in the isolated rat liver. Am J Physiol 1993; 264: G1103– G1111.MEDLINE 82 Koeppel TA, Trauner M, Baas JC, Thies JC, Schlosser SF, Post S, Gebhard MM, et al. Extrahepatic biliary obstruction impairs microvasculature perfusion and increases leukocyte adhesion in rat liver. Hepatology 1997; 26: 1085– 1091.MEDLINE Citing Literature Volume28, Issue1July 1998Pages 253-260 ReferencesRelatedInformation

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