PHARMACOLOGY OF HYPOTHALAMIC REGULATORY PEPTIDES
1976; Wiley; Volume: 5; Issue: s1 Linguagem: Inglês
10.1111/j.1365-2265.1976.tb03834.x
ISSN1365-2265
AutoresWylie Vale, Catherine Rivier, Marvin R. Brown, Juhani Leppäluoto, Nick Ling, MIKE MONAHAN, Jean Rivier,
Tópico(s)Receptor Mechanisms and Signaling
ResumoClinical EndocrinologyVolume 5, Issue s1 p. s261-s273 PHARMACOLOGY OF HYPOTHALAMIC REGULATORY PEPTIDES WYLIE VALE, WYLIE VALE The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorCATHERINE RIVIER, CATHERINE RIVIER The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorMARVIN BROWN, MARVIN BROWN The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorJUHANI LEPPALUOTO, JUHANI LEPPALUOTO The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorNICK LING, NICK LING The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorMIKE MONAHAN, MIKE MONAHAN The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorJEAN RIVIER, JEAN RIVIER The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this author WYLIE VALE, WYLIE VALE The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorCATHERINE RIVIER, CATHERINE RIVIER The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorMARVIN BROWN, MARVIN BROWN The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorJUHANI LEPPALUOTO, JUHANI LEPPALUOTO The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorNICK LING, NICK LING The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorMIKE MONAHAN, MIKE MONAHAN The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this authorJEAN RIVIER, JEAN RIVIER The Salk Institute for Biological Studies, La Jolla, CaliforniaSearch for more papers by this author First published: February 1976 https://doi.org/10.1111/j.1365-2265.1976.tb03834.xCitations: 48 Dr W. Vale, The Salk Institute for Biological Studies, La Jolla, California 92037, U.S.A. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References Arimura, A., Sato, H., Coy, D. & Schally, A.V. (1975) Radioimmunoassay for GH-release inhibiting hormone. Proceedings of the Society for Experimental Biology and Medicine, 148, 784–789. 10.3181/00379727-148-38631 CASPubMedWeb of Science®Google Scholar Besser, G.M., Mortimer, C.H., McNeilly, A.S., Thorner, M.O., et al. (1974) Long term infusion of growth hormone release inhibiting hormone in acromegaly: effects on pituitary and pancreatic hormones. British Medical Journal, iv, 622–627. 10.1136/bmj.4.5945.622 Google Scholar Brazeau, P., Vale, W., Burgus, R., Ling, N., Butcher, M., Rivier, J. & Guillemin, R. (1973) Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. Science, 179, 77–79. 10.1126/science.179.4068.77 CASPubMedWeb of Science®Google Scholar Burgus, R., Brazeau, P. & Vale, W. (1973) Isolation and determination of the primary structure of somatostatin, a somatotropin release inhibiting factor of ovine hypothalamic origin. Advances in Human Growth Hormone Research (ed. by S. Raiti), Vol. 1, pp. 144–158. U.S. Goverment Printing Office, DHEW, Publ. No. (NIH) 74612. Google Scholar Corbin, A. & Beattie, B. (1975) Inhibition of the pre-ovulatory proestrous gonadotropin surge, ovulation and pregnancy with a peptide analogue of luteinizing hormone releasing hormone. Endocrine Research Communications, 2, 1–23. 10.3109/07435807509053836 CASPubMedWeb of Science®Google Scholar Coy, D., Coy, E., Schally, A.V., Vilchez-Martinez, J., Hirotsu, Y., & Arimura, A. (1974) Synthesis and biological properties of [D-Ala-6, Des-Gly-NH2-10]-LH-RH ethylamide, a peptide with greatly enhanced LH- and FSH-releasing activity. Biochemical and Biophysical Research Communications, 57, 335–340. 10.1016/0006-291X(74)90934-6 CASPubMedWeb of Science®Google Scholar Fujino, M., Yamazaki, I., Kobayashi, S., Fukada, T., Shinagawa, S. & Nakayama, R. (1974) Some analogs of luteinizing hormone releasing hormone (LH-RH) having intense ovulation-inducing activity. Biochemical and Biophysical Reserach Communications, 57, 1248–1256. 10.1016/0006-291X(74)90830-4 CASPubMedWeb of Science®Google Scholar Gerich, J. & Guillemin, R. (1976) Somatostatin: physiological and clinical significance. Annual Review of Medicine (in press). PubMedWeb of Science®Google Scholar Gerich, J. E., Lorenzi, M., Schneider, V., Karam, J., Rivier, J. & Guillemin, R. (1974) Effects of somatostatin on plasma glucose and glucagon levels in human diabetes mellitus: pathophysiology and therapeutic implications. New England Journal of Medicine, 291, 544–547. 10.1056/NEJM197409122911102 CASPubMedWeb of Science®Google Scholar Hinkle, P.M., Woroch, E.L. & Tashjian, A. H. (1974) Receptor-binding affinities and biological activities of analogs of thyrotropin-releasing hormone in prolactin-producing pituitary cells in culture. Journal of Biological Chemistry, 249, 3085–3090. CASPubMedWeb of Science®Google Scholar Holladay, L.A. & Puett, D. (1975) Somatostatin conformation. Endocrinology, 96, 252A. Google Scholar Koch, Y., Baram, T. & Cholsieng, A. P. (1974) Enzymatic degradation of luteinizing hormone-releasing hormone (LH-RH) by hypothalamic tissue. Biochemical and Biophysical Research Communications, 61, 95–103. 10.1016/0006-291X(74)90539-7 CASPubMedWeb of Science®Google Scholar Ling, N. & Vale, W. (1975) Analogs of luteinizing hormone releasing factor (LRF). Synthesis and biological activity of [(N*-Me)Leu7]LRF. Biochemical and Biophysical Research Communications, 63, 801–806. 10.1016/S0006-291X(75)80454-2 CASPubMedWeb of Science®Google Scholar Ling, N., Burgus, R., Rivier, J., Vale, W. & Brazeau, P. (1973) The use of mass spectrometry in deducing the sequence of somatostatin-a hypothalamic polypeptide that inhibits the secretion of growth hormone. Biochemical and Biophysical Research Communications, 50, 127–133. 10.1016/0006-291X(73)91073-5 CASPubMedWeb of Science®Google Scholar Marks, N. & Stern, F. (1974) Enzymatic mechanisms for the inactivation of luteinizing hormone-releasing hormone (LH-RH). Biochemical and Biophysical Research Communications, 61, 1458–1463. 10.1016/S0006-291X(74)80447-X CASPubMedWeb of Science®Google Scholar Marks, N. & Stern, F. (1975) Inactivation of somatostatin (GH-RH) and its analogs by crude and partially purified rat brain extracts. FEBS Letters, 55, 220–224. 10.1016/0014-5793(75)80996-3 CASPubMedWeb of Science®Google Scholar Monahan, M., Rivier, J., Vale, W., Guillemin, R. & Burgus, R. (1972) [Gly2]LRF and des-His2-LRF. The synthesis, purification and characterization of two LRF analogues antagonistic to LRF. Biochemical and Biophysical Research Communications, 47, 551–556. 10.1016/0006-291X(72)90914-X CASPubMedWeb of Science®Google Scholar Monahan, M., Amoss, M., Anderson, H. & Vale, W. (1973a) Synthetic analogs of the hypothalamic luteinizing hormone releasing factor with increased agonist or antagonist properties. Biochemistry, 12, 4616–4620. 10.1021/bi00747a012 CASPubMedWeb of Science®Google Scholar Monahan, M., Vale, W., Rivier, C., Grant, G. & Guillemin, R. (1973b) Analogues of LRF with inhibitory action or greater potency than the natural decapeptide hormone. Endocrinology, 93, 1974A. Google Scholar Patel, Y. & Reichlin, S. (1975) Endocrinology (in press). Google Scholar Redding, T.W. & Shally, A. V. (1967) Studies on the inactivation of thyrotropin-releasing hormone (TRH). Proceedings of the Society for Experimental Biology and Medicine, 131, 415–420. 10.3181/00379727-131-33891 PubMedWeb of Science®Google Scholar Rees, R., Foell, T., Chai, S., & Grant, N. (1974) Synthesis and biological activities of analogs of the luteinizing hormone releasing hormone (LH-RH) modified in position 2. Journal of Medicinal Chemistry, 17, 1016–1019. 10.1021/jm00255a025 CASPubMedWeb of Science®Google Scholar Rivier, J., Monahan, M., Vale, W., Grant, G., Amoss, M., Blackwell, R., Guillemin, R. & Burgus, R. (1972) Solid-phase peptide synthesis on a benzyhydrylamine resin of LRF (luteinizing hormone releasing factor) and analogues, including antagonists. Chimia, 26, 300–303. CASWeb of Science®Google Scholar Rivier, C. Vale, W. (1974) In vivo stimulation of prolactin secretion in the rat by thyrotropin releasing factor and related peptides and hypothalamic extracts. Endocrinology, 95, 978–983. 10.1210/endo-95-4-978 CASPubMedWeb of Science®Google Scholar Rivier, J., Brown, M. & Vale, W. (1975a) D-Trp8-Somatostatin: an analog of somatostatin more potent than the native molecule. Biochemical and Biophysical Research Communications, 65, 746–751. 10.1016/S0006-291X(75)80208-7 CASPubMedWeb of Science®Google Scholar Rivier, J., Brazeau, P., Vale, W., Ling, N., Burgus, R., Gilon, C., Yardley, J. & Guillemin, R. (1973) Synthèse totale par phase solide d'un tétradécapeptide ayant les properietés chimiques et biologiques de la somatostatine. Comptes Rendus Hebdomadaire des Séances de l' Académie des Sciences, 276, 2737–2740. CASPubMedWeb of Science®Google Scholar Rivier, J., Ling, N., Monahan, M., Rivier, C., Brown, M. & Vale, W. (1975b) Luteinizing hormone releasing factor and somatostatin analogs. In Peptides: Chemistry, Structure and Biology (ed. by R. Walter and J. Meienhofer). Ann Arbor Science Publ. (in press). Google Scholar Roth, J., Kahn, R., Lesniak, M., Gorden, P., DE Meyts, P., Megyesi, K., Neville, D., Gavin, J. Soll, A., Freuchet, P., Goldfine, I., Bar, R. & Archer, J. (1975) Receptors for insulin, NSILA-s and growth hormone: applications to disease states in man. Recent Progress in Hormone Research, 31, 95–125. CASPubMedGoogle Scholar Sievertsson, H., Chang, J-K., von Klandy, A., Bongentoft, C., Currie, B., Folkers, K. & Bowers, C. (1972) Two syntheses of the luteinizing hormone releasing hormone of the hypothalamus. Journal of Medicinal Chemistry, 15, 222–226. 10.1021/jm00273a003 CASPubMedWeb of Science®Google Scholar Vale, W., Burgus, R., Dunn, T.F. & Guillemin, R. (1971a) In vitro plasma inactivation of thyrotropin releasing factor (TRF) and related peptides. Its inhibition by various means and by the synthetic dipeptide PCA-His-OMe. Hormones, 2, 193–203. 10.1159/000178234 CASPubMedWeb of Science®Google Scholar Vale, W., Rivier, J. & Burgus, R. (1971b) TRF (Thyrotropin releasing factor) analogues: II. pGlu-N31m Me-His-Pro-NH2: a synthetic analgoue with specific activity greater than that of TRF. Endocrinology, 89, 1485–1488. 10.1210/endo-89-6-1485 CASPubMedWeb of Science®Google Scholar Vale, W., Brazeau, P., Grant, G., Nussey, A., Burgus, R., Rivier, J., Ling, N. & Guillemin, R. (1972a) Premières observations sur le mode d'action de la somatostatine un facteur hypothalamique qui inhibe la sécrétion de l'hormone de croissance. Comptes Rendus Hebdomadaire des Séances de l'Académie des Sciences, 275, 2913–2915. CASPubMedWeb of Science®Google Scholar Vale, W., Grant, G., Rivier, J., Monahan, M., Amoss, M., Blackwell, N., Burgus, R. & Guillemin, R. (1972b) Synthetic polypeptide antagonists of the hypothalamic luteinizing hormone releasing factor. Science, 176, 933–934. 10.1126/science.176.4037.933 CASPubMedWeb of Science®Google Scholar Vale, W., Grant, G. & Guillemin, R. (1973a) Chemistry of the hypothalamic releasing factors-studies on structure-function relationships. Frontiers in Neuroendocrinology (ed. by L. Martini and W. Ganong), pp. 375–413. Oxford University Press, New York . Google Scholar Vale, W., Brazeau, P., Rivier, C., Rivier, J. & Gullemin, R. (1973b) Biological studies with somatostatin. Advances in Human Growth Hormone Research, (ed. by S. Raiti), Vol. 1, pp. 159–182. U.S. Government Printing Office, DHEW, Publ. No. (NIH) 74612. Google Scholar Vale, W. & Grant, G. (1974) In vitro pituitary hormone secretion for hypophysiotropic substances. Methods in Enzymology Hormones and Cyclic Nucleotides, (ed. by B. W. O'Malley and J. G. Hardman), Vol. 37, chap. 15, pp. 82–93. Academic Press, New York . Google Scholar Vale, W. & Rivier, C. (1975) Hypothalamic and hypophysiotropic hormones. Handbook of Psychopharmacology, pp. 196–237. Plenum Press, New York . Google Scholar Vale, W., Rivier, C., Rivier, J., Ling, N., Monahan, M. & Guillemin, R. (1975a) Synthetic and native substances modifying secretion of gonadotropins. Endocrinology, 96, 99A. Google Scholar Vale, W., Brazeau, P., Rivier, C., Brown, M., Boss, B., Rivier, J., Burgus, R., Ling, N. & Guillemin, R. (1975b) Somatostatin. Recent Progress in Hormone Research, 31, 365–397. CASPubMedGoogle Scholar Vilchez-Martinez, J.A., Coy, D.H., Coy, E., DE LA Cruz, A., Nishi, N. & Schally, A.V. (1975) Prolonged inhibition of gonadotropin release and suppression of ovulation by synthetic antagonists of LH-RH. Endocrinology, 96, 354A. Google Scholar Vilchez-Martinez, J.A., Coy, D.H., Arimura, A., Coy, E.J., Hirotsu, Y. & Schally, A. V. (1974) Synthesis and biological properties of [Leu-6, Des-Gly-NH210]-LH-RH ethylamide. Biochemical and Biophysical Research Communications, 59, 1226–1232. 10.1016/0006-291X(74)90445-8 CASPubMedWeb of Science®Google Scholar Citing Literature Volume5, Issues1February 1976Pages s261-s273 ReferencesRelatedInformation
Referência(s)