Motor Proteins at Work for Nanotechnology
2007; American Association for the Advancement of Science; Volume: 317; Issue: 5836 Linguagem: Inglês
10.1126/science.1139570
ISSN1095-9203
AutoresM. G. L. van den Heuvel, Cees Dekker,
Tópico(s)Cardiomyopathy and Myosin Studies
ResumoThe biological cell is equipped with a variety of molecular machines that perform complex mechanical tasks such as cell division or intracellular transport. One can envision employing these biological motors in artificial environments. We review the progress that has been made in using motor proteins for powering or manipulating nanoscale components. In particular, kinesin and myosin biomotors that move along linear biofilaments have been widely explored as active components. Currently realized applications are merely proof-of-principle demonstrations. Yet, the sheer availability of an entire ready-to-use toolbox of nanosized biological motors is a great opportunity that calls for exploration.
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