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The TATA-binding protein: a central role in transcription by RNA polymerases I, II and III

1992; Elsevier BV; Volume: 8; Issue: 8 Linguagem: Inglês

10.1016/0168-9525(92)90255-3

1362-4555

R. White, Stephen P. Jackson,

RNA and protein synthesis mechanisms

The TATA-box-binding protein, first noted for its association with the general transcription factor TFIID, has recently been shown to be required for transcription by all three classes of nuclear RNA polymerase found in eukaryotes. As such, it plays a unique and pivotal role in gene expression in higher organisms.