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Organocatalytic strategies for the asymmetric functionalization of indoles

2010; Royal Society of Chemistry; Volume: 39; Issue: 11 Linguagem: Inglês

10.1039/b923063g

1460-4744

Giuseppe Bartoli, Giorgio Bencivenni, Renato Dalpozzo,

Oxidative Organic Chemistry Reactions

The desire for new synthetic methodologies for the rapid construction of enantiomerically pure substituted indole has been a fruitful driving force for chemical research in the last few years. This research line has produced a stunning array of enantioselective technologies either metal or organocatalyzed. This critical review documents the development of organocatalytic indole alkylation strategies, until the end of 2009 (127 references).