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Highly Emissive Self‐assembled Organic Nanoparticles having Dual Color Capacity for Targeted Immunofluorescence Labeling

2008; Volume: 20; Issue: 6 Linguagem: Inglês

10.1002/adma.200701601

1521-4095

Hyong‐Jun Kim, Jiseok Lee, Tae Whan Kim, Taek Seung Lee, Jinsang Kim,

Advanced biosensing and bioanalysis techniques

A new benzoxazole molecule has been synthesized and self-assembled with functionalized diacetylene molecules to obtain well-defined nanoparticles of 80 nm diameter. The nanoparticles show enhanced fluorescence emission of 38% quantum yield compared to 3% in THF solution. Selective targeting and dual color visualization of patterned avidin arrays were achieved by using these nanoparticles to demonstrate their promising application for immunofluorescence labeling. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2089/2008/adma200701601_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.