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Effects of Oral N-Acetylcysteine on Plasma Homocysteine and Whole Blood Glutathione Levels in Healthy, Non-pregnant Women

2002; De Gruyter; Volume: 40; Issue: 5 Linguagem: Inglês

10.1515/cclm.2002.086

1437-4331

Eva Maria Roes, Maarten T.M. Raijmakers, Wilbert H.M. Peters, Eric A.P. Steegers,

Pregnancy and preeclampsia studies

Oral N-acetylcysteine supplementation in nine young healthy females induced a quick and highly significant decrease in plasma homocysteine levels and an increase in whole blood concentration of the antioxidant glutathione. N -acetylcysteine impresses as an efficient drug in lowering homocysteine concentration and might be beneficial for individuals with hyperhomocysteinemia who are at increased risk of cardiovascular disease.