Portal de Periódicos da CAPES

Small‐Molecule Regulators of Human Stem Cell Self‐Renewal

2011; Wiley; Volume: 12; Issue: 6 Linguagem: Inglês

10.1002/cbic.201000734

1439-7633

Laure C. Bouchez, Anthony E. Boitano, Lorenzo de Lichtervelde, Russell D. Romeo, Michael P. Cooke, Peter G. Schultz,

Neonatal Respiratory Health Research

A cell-based phenotypic screen using primary CD34+ cells identified novel regulators of hematopoietic stem cell (HSC) fate. These compounds expand cord-blood-derived HSCs by acting as potent antagonists of the aryl hydrocarbon receptor. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.