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Quantitative Determination of Metadrenaline and Normetadrenaline in Human Urine

1961; Tohoku University; Volume: 74; Issue: 1 Linguagem: Inglês

10.1620/tjem.74.105

1349-3329

KAORU YOSHINAGA, Chuichi Itoh, Nozomu Ishida, Tatsuo Sato, Yasuo Wada,

Eicosanoids and Hypertension Pharmacology

1. A method of measuring the concentrations of M and NM in human urine was described. 2. The normal human excretes daily 100_??_300 μg. of M and almost the same amount of NM in the urine. The concentrations of M and NM in the urine from patients with Graves' disease, essential hypertension, primary aldosteronism and Parkinsonism were within the normal ragne. 3. The concentrations of M and NM in the urine from patients with phaeochromocytoma were abnormally high.