Exclusion of the stomatin, ?-adducin and ?-adducin loci in a large kindred with dehydrated hereditary stomatocytosis
1999; Wiley; Volume: 60; Issue: 1 Linguagem: Inglês
10.1002/(sici)1096-8652(199901)60
ISSN1096-8652
AutoresDavid Scott Innes, John H. Sinard, Diana M. Gilligan, L. Michael Snyder, Patrick G. Gallagher, Jon S. Morrow,
Tópico(s)Blood properties and coagulation
ResumoDefects in stomatin, α-and β-adducin have been implicated in erythrocyte disorders of cation permeability. We performed linkage analysis of the genetic loci for these proteins in a large kindred with xerocytosis (dehydrated hereditary stomatocytosis). Using polymerase chain reaction-based genotyping techniques, all three loci are excluded as disease gene candidates. Am. J. Hematol. 60:72–74, 1999. © 1999 Wiley-Liss, Inc.
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