Thrombocytosis in giant cell arteritis.
1980; BMJ; Volume: 39; Issue: 3 Linguagem: Inglês
10.1136/ard.39.3.298-a
ISSN1468-2060
Autores Tópico(s)Platelet Disorders and Treatments
ResumoThrombocytosis in giant cell arteritisSir, The interesting paper of Bergstrom and colleagues' comes to the conclusion that thombocytosis in giant cell arteritis is reactive to the inflammation present in this disease.We came by other ways to the same conclusion.24We evaluated platelet counts in 146 cases of rheumatoid arthritis, in 43 cases ofjuvenile chronic arthritis (22 cases of juvenile rheumatoid arthritis 6 Still's patients, and 15 cases of juvenile mono-oligoarthritis), in 7 patients with Sj6gren's syndrome, in 41 with progressive systemic sclerosis, in 11 with rheumatic polymyalgia with or without Horton's arteritis, in 29 with ankylosing spondy- litis, in 34 with psoriatic arthritis, and in 17withgout.In all the groups of patients, except for juvenile mono-oligo- arthritis, we found mean platelet counts greater than those in control subjects 214 500 ± 32 886/mms (214 ± 33 x 109/1) by the method of Palumbo and DiniO.A clear thrombocytosis was present only in a percentage of the patients of the different groups.In these thrombocytosis patients there was a higher disease activity.Furthermore, we found a positive correlation between ESR and platelet count, serum mucoproteins, and platelet count; and a negative correlation between serum iron and platelet count.Therefore it is possible to assume that thrombo- cytosis is an inflammation index in rheumatic and con- nective tissue diseases.The researches of Bergstrom and colleagues are an elegant confirmation of this assumption.
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