Chromosome workshop: Chromosomes 11, 14, and 15
1999; Wiley; Volume: 88; Issue: 3 Linguagem: Inglês
10.1002/(sici)1096-8628(19990618)88
ISSN1096-8628
AutoresNick Craddock, Corinne Lendon, Sven Cichon, Rob Culverhouse, Sevilla D. Detera‐Wadleigh, Rebecca S. Devon, Steve Faraone, Tatiana Foroud, Pablo V. Gejman, Sherry Leonard, Melvin G. McInnis, Michael J. Owen, Brien P. Riley, C P Armstrong, Nick Barden, Christine Van Broeckhoven, H. Ewald, Susan E. Folstein, Daniela S. Gerhard, David Goldman, Hugh Gurling, John R. Kelsoe, Doug Levinson, Walter Muir, Ann Philippe, Ann E. Pulver, Dieter B. Wildenauer,
Tópico(s)Genomic variations and chromosomal abnormalities
ResumoAmerican Journal of Medical GeneticsVolume 88, Issue 3 p. 244-254 Chromosome workshop: Chromosomes 11, 14, and 15 Nick Craddock, Corresponding Author Nick Craddock Chair n.craddock@bham.ac.uk Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, U.K.Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Mindelsohn Way, Birmingham B15 2QZ U.K.Search for more papers by this authorCorinne Lendon, Corinne Lendon Co-Chair Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, U.K.Search for more papers by this authorSven Cichon, Sven Cichon Participant Institute of Human Genetics, University of Bonn, GermanySearch for more papers by this authorRob Culverhouse, Rob Culverhouse Participant Department of Psychiatry, Washington University, St. Louis, MissouriSearch for more papers by this authorSevilla Detera-Wadleigh, Sevilla Detera-Wadleigh Participant National Institute of Mental Health, Bethesda, MarylandSearch for more papers by this authorRebecca Devon, Rebecca Devon Participant MRC Human Genetics Unit, Western General Hospital, Edinburgh, U.K.Search for more papers by this authorSteve Faraone, Steve Faraone Participant Department of Psychiatry, Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorTatiana Foroud, Tatiana Foroud Participant Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IndianaSearch for more papers by this authorPablo Gejman, Pablo Gejman Participant National Institute of Mental Health, Bethesda, MarylandSearch for more papers by this authorSherry Leonard, Sherry Leonard Participant Department of Psychiatry, University Colorado Health Sciences Center, Boulder, ColoradoSearch for more papers by this authorMelvin McInnis, Melvin McInnis Participant Johns Hopkins University, Baltimore, MarylandSearch for more papers by this authorMichael J. Owen, Michael J. Owen Participant Neuropsychiatric Genetics Unit, University of Wales College of Medicine, Cardiff, U.K.Search for more papers by this authorBrien Riley, Brien Riley Participant Department of Psychological Medicine, Institute of PsychiatrySearch for more papers by this authorChris Armstrong, Chris Armstrong Contributor Department of Psychiatry, Washington University School of Medicine, St. Louis, MissouriSearch for more papers by this authorNick Barden, Nick Barden Contributor Department of Neuroscience, Laval University Research CenterSearch for more papers by this authorChristine van Broeckhoven, Christine van Broeckhoven Contributor Department of Biochemistry, University of Antwerp, BelgiumSearch for more papers by this authorHenrik Ewald, Henrik Ewald Contributor Department of Psychiatric Demography, Psychiatric Hospital in Aarhus, DenmarkSearch for more papers by this authorSusan Folstein, Susan Folstein Contributor Tufts University School of Medicine, Boston, MassachusettsSearch for more papers by this authorDaniela Gerhard, Daniela Gerhard Contributor Department of Genetics, Washington University School of Medicine, St. Louis, MissouriSearch for more papers by this authorDavid Goldman, David Goldman Contributor NIAAA, Potomac, MarylandSearch for more papers by this authorHugh Gurling, Hugh Gurling Contributor Department of Psychiatry, University College & Middlesex School of MedicineSearch for more papers by this authorJohn Kelsoe, John Kelsoe Contributor Department of Psychiatry, University California, San Diego, CaliforniaSearch for more papers by this authorDoug Levinson, Doug Levinson Contributor Department of Psychiatry, Allegheny University Health Sciences, Philadelphia, PennsylvaniaSearch for more papers by this authorWalter Muir, Walter Muir Contributor MRC Human Genetics Unit, Western General Hospital, Edinburgh, U.K.Search for more papers by this authorAnn Philippe, Ann Philippe Contributor INSERM, Paris, FranceSearch for more papers by this authorAnn Pulver, Ann Pulver Contributor Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MarylandSearch for more papers by this authorDieter Wildenauer, Dieter Wildenauer Contributor Molecular Genetics Laboratory, University of Bonn, GermanySearch for more papers by this author Nick Craddock, Corresponding Author Nick Craddock Chair n.craddock@bham.ac.uk Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, U.K.Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Mindelsohn Way, Birmingham B15 2QZ U.K.Search for more papers by this authorCorinne Lendon, Corinne Lendon Co-Chair Division of Neuroscience, University of Birmingham, Queen Elizabeth Psychiatric Hospital, Birmingham, U.K.Search for more papers by this authorSven Cichon, Sven Cichon Participant Institute of Human Genetics, University of Bonn, GermanySearch for more papers by this authorRob Culverhouse, Rob Culverhouse Participant Department of Psychiatry, Washington University, St. Louis, MissouriSearch for more papers by this authorSevilla Detera-Wadleigh, Sevilla Detera-Wadleigh Participant National Institute of Mental Health, Bethesda, MarylandSearch for more papers by this authorRebecca Devon, Rebecca Devon Participant MRC Human Genetics Unit, Western General Hospital, Edinburgh, U.K.Search for more papers by this authorSteve Faraone, Steve Faraone Participant Department of Psychiatry, Harvard Medical School, Boston, MassachusettsSearch for more papers by this authorTatiana Foroud, Tatiana Foroud Participant Department of Medical & Molecular Genetics, Indiana University School of Medicine, Indianapolis, IndianaSearch for more papers by this authorPablo Gejman, Pablo Gejman Participant National Institute of Mental Health, Bethesda, MarylandSearch for more papers by this authorSherry Leonard, Sherry Leonard Participant Department of Psychiatry, University Colorado Health Sciences Center, Boulder, ColoradoSearch for more papers by this authorMelvin McInnis, Melvin McInnis Participant Johns Hopkins University, Baltimore, MarylandSearch for more papers by this authorMichael J. Owen, Michael J. Owen Participant Neuropsychiatric Genetics Unit, University of Wales College of Medicine, Cardiff, U.K.Search for more papers by this authorBrien Riley, Brien Riley Participant Department of Psychological Medicine, Institute of PsychiatrySearch for more papers by this authorChris Armstrong, Chris Armstrong Contributor Department of Psychiatry, Washington University School of Medicine, St. Louis, MissouriSearch for more papers by this authorNick Barden, Nick Barden Contributor Department of Neuroscience, Laval University Research CenterSearch for more papers by this authorChristine van Broeckhoven, Christine van Broeckhoven Contributor Department of Biochemistry, University of Antwerp, BelgiumSearch for more papers by this authorHenrik Ewald, Henrik Ewald Contributor Department of Psychiatric Demography, Psychiatric Hospital in Aarhus, DenmarkSearch for more papers by this authorSusan Folstein, Susan Folstein Contributor Tufts University School of Medicine, Boston, MassachusettsSearch for more papers by this authorDaniela Gerhard, Daniela Gerhard Contributor Department of Genetics, Washington University School of Medicine, St. Louis, MissouriSearch for more papers by this authorDavid Goldman, David Goldman Contributor NIAAA, Potomac, MarylandSearch for more papers by this authorHugh Gurling, Hugh Gurling Contributor Department of Psychiatry, University College & Middlesex School of MedicineSearch for more papers by this authorJohn Kelsoe, John Kelsoe Contributor Department of Psychiatry, University California, San Diego, CaliforniaSearch for more papers by this authorDoug Levinson, Doug Levinson Contributor Department of Psychiatry, Allegheny University Health Sciences, Philadelphia, PennsylvaniaSearch for more papers by this authorWalter Muir, Walter Muir Contributor MRC Human Genetics Unit, Western General Hospital, Edinburgh, U.K.Search for more papers by this authorAnn Philippe, Ann Philippe Contributor INSERM, Paris, FranceSearch for more papers by this authorAnn Pulver, Ann Pulver Contributor Department of Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MarylandSearch for more papers by this authorDieter Wildenauer, Dieter Wildenauer Contributor Molecular Genetics Laboratory, University of Bonn, GermanySearch for more papers by this author First published: 25 October 2002 https://doi.org/10.1002/(SICI)1096-8628(19990618)88:3 3.0.CO;2-1Citations: 42AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract This report describes linkage data presented at the Workshop on Chromosomes 11, 14, and 15 at the Sixth World Congress of Psychiatric Genetics in Bonn, Germany, together with relevant linkage data submitted to the chair and co-chair, and it is presented in the context of the previous literature concerning these chromosomes. We have attempted to collate current linkage data to provide a guide to potentially interesting findings on chromosomes 11, 14, and 15 for the phenotypes of bipolar disorder, schizophrenia, alcoholism, autism, and spelling and reading disability. We discuss methodological limitations and provide chromosome ideograms and tables summarizing findings to date. The most promising region currently appears to be 15q13-q15 in the region of the alpha 7 nicotinic receptor for the phenotype of schizophrenia (and, perhaps, more generally for functional psychosis). Additionally, 15q11-q13 in the region of GABRB3 holds interest as a potential site of a susceptibility gene for autism. Two regions on chromosome 11, 11p15 in the region of tyrosine hydroxylase gene and 11q22-q23 in the region of DRD2, continue to retain some interest for functional psychosis. Am. J. Med. Genet. (Neuropsychiatr. Genet.) 88:244–254, 1999. © 1999 Wiley-Liss, Inc. Citing Literature Volume88, Issue318 June 1999Pages 244-254 RelatedInformation
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