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GCWIND: a microcomputer program for identifying open reading frames according to codon positional G + C content

1992; Oxford University Press; Volume: 8; Issue: 5 Linguagem: Inglês

10.1093/bioinformatics/8.5.521

1367-4811

Denis C. Shields, Desmond G. Higgins, Paul M. Sharp,

Bacterial Genetics and Biotechnology

GCWIND is a microcomputer (IBM-PC compatible) program for the identification of protein-coding open reading frames. The program is similar to the FRAME program, but the latter has only been implemented for a specialized graphics package. The base compositions (%G+C) for each of the three possible reading phases through the DNA sequence are displayed separately, together with the positions of potential translation initiation and termination codons (on the leading and complementary strands), to provide an immediate representation of those regions within the sequence that have coding potential.