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Developmental Changes in Human Fetal Testicular Cell Numbers and Messenger Ribonucleic Acid Levels during the Second Trimester

2007; Oxford University Press; Volume: 92; Issue: 12 Linguagem: Inglês

10.1210/jc.2007-1690

1945-7197

P.J. O'Shaughnessy, PJ Baker, Ana Monteiro, Sarah Cassie, Siladitya Bhattacharya, Paul Fowler,

Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities

Context: Normal fetal testis development is essential for masculinization and subsequent adult fertility. The second trimester is a critical period of human testicular development and masculinization, but there is a paucity of reliable developmental data.