Artigo Revisado por pares

Suppression of Immunity by Stress: Effect of a Graded Series of Stressors on Lymphocyte Stimulation in the Rat

1981; American Association for the Advancement of Science; Volume: 213; Issue: 4514 Linguagem: Inglês

10.1126/science.6973822

ISSN

1095-9203

Autores

Steven E. Keller, Jay M. Weiss, Steven J. Schleifer, N. E. Miller, Marvin Stein,

Tópico(s)

Stress Responses and Cortisol

Resumo

In rats a graded series of stressors produced progressively greater suppression of lymphocyte function, as measured by the number of circulating lymphocytes and by phytohemagglutinin stimulation of lymphocytes in whole blood and isolated cultures. This evidence suggests that stress suppresses immunity in proportion to the intensity of the stressor.

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