Leishmaniasis among Gold Miners, French Guiana
2006; Centers for Disease Control and Prevention; Volume: 12; Issue: 7 Linguagem: Inglês
10.3201/eid1207.051466
ISSN1080-6059
AutoresBrice Rotureau, Michel Joubert, E. Clyti, Félix Djossou, Bernard Carme,
Tópico(s)Parasites and Host Interactions
ResumoLeishmaniasis among Gold Miners, French GuianaTo the Editor: In 2004, the Cayenne General Hospital and public health centers recorded 348 new cases of cutaneous leishmaniasis (CL) in French Guiana (1).A case of CL was considered confirmed if cutaneous lesions were present for >2 weeks; the patient had a compatible epidemiologic history; and microscopic examination of dermal scrapings, parasite cultivation, or both showed positive results for Leishmania.According to the population estimate given by the French National Institute for Statistics and Economical Studies (INSEE, Cayenne), the incidence of CL in 2004 was 0.2%-0.4% and has been relatively stable since 1979 (2,3).However, when the annual number of cases per village were examined, new CL cases were heterogeneously distributed.Saint Elie, a gold-mining village in the inland neotropical forest, had an apparent incidence rate of 25.9% in 2004 and 28.9% in 2005 (Figure); risk for infection in this village was, on average, 65× higher than anywhere else in French Guiana.We tested samples from 12 random CL patients with a Leishmania-specific polymerase chain reaction-restriction fragment length polymorphism test that targeted the internal transcribed spacer 1 of ribosomal RNA genes with primers SSU-12103-D (5′-
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