Revisão Acesso aberto Revisado por pares

Managing Incidental Findings in Human Subjects Research: Analysis and Recommendations

2008; Cambridge University Press; Volume: 36; Issue: 2 Linguagem: Inglês

10.1111/j.1748-720x.2008.00266.x

ISSN

1748-720X

Autores

Susan M. Wolf, Frances Lawrenz, Charles A. Nelson, Jeffrey Kahn, Mildred K. Cho, Ellen Wright Clayton, Joel G. Fletcher, Michael Georgieff, Dale E. Hammerschmidt, Kathy Hudson, Judy Illes, Vivek Kapur, Moira A. Keane, Barbara A. Koenig, Bonnie S. LeRoy, Elizabeth G. McFarland, Jordan Paradise, Lisa S. Parker, Sharon F. Terry, Brian G. Van Ness, Benjamin S. Wilfond,

Tópico(s)

Global Cancer Incidence and Screening

Resumo

Researchers, institutional review boards (IRBs), participants in human subjects research, and their families face an important but largely neglected problem — how should incidental findings (IFs) be managed in human subjects research. If researchers unexpectedly stumble upon information of potential health or reproductive significance, should they seek expert evaluation, contact the participant’s physician, tell the research participant, or respond with some combination? What should consent forms and the entire consent process say about how IFs will be handled in research? What should IRBs require?

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