Bilateral mirror writing movements (mirror dystonia) in a patient with writer's cramp: Functional correlates
2005; Wiley; Volume: 21; Issue: 5 Linguagem: Inglês
10.1002/mds.20736
ISSN1531-8257
AutoresMarcelo Merello, Silvina Carpintiero, Ángel Cammarota, Francisco Meli, R. Leiguarda,
Tópico(s)Botulinum Toxin and Related Neurological Disorders
ResumoMovement DisordersVolume 21, Issue 5 p. 683-689 Brief Report Bilateral mirror writing movements (mirror dystonia) in a patient with writer's cramp: Functional correlates Marcelo Merello MD, PhD, Corresponding Author Marcelo Merello MD, PhD [email protected] Movement Disorders Section, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, Argentina Neurology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaRaul Carrea Institute for Neurological Research (FLENI), Montañeses 2325, C1428AQK Buenos Aires, ArgentinaSearch for more papers by this authorSilvina Carpintiero PhD, Silvina Carpintiero PhD Radiology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaSearch for more papers by this authorAngel Cammarota MD, Angel Cammarota MD Movement Disorders Section, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, Argentina Neurology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaSearch for more papers by this authorFrancisco Meli MD, Francisco Meli MD Radiology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaSearch for more papers by this authorRamon Leiguarda MD, Ramon Leiguarda MD Neurology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaSearch for more papers by this author Marcelo Merello MD, PhD, Corresponding Author Marcelo Merello MD, PhD [email protected] Movement Disorders Section, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, Argentina Neurology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaRaul Carrea Institute for Neurological Research (FLENI), Montañeses 2325, C1428AQK Buenos Aires, ArgentinaSearch for more papers by this authorSilvina Carpintiero PhD, Silvina Carpintiero PhD Radiology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaSearch for more papers by this authorAngel Cammarota MD, Angel Cammarota MD Movement Disorders Section, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, Argentina Neurology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaSearch for more papers by this authorFrancisco Meli MD, Francisco Meli MD Radiology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaSearch for more papers by this authorRamon Leiguarda MD, Ramon Leiguarda MD Neurology Department, Raul Carrea Institute for Neurological Research FLENI, Buenos Aires, ArgentinaSearch for more papers by this author First published: 09 December 2005 https://doi.org/10.1002/mds.20736Citations: 18Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Abstract A recent prospective analysis on writer's cramp showed that up to 44.6% of patients in a series of 65 presented mirror dystonia, defined as involuntary movements of the resting hand, abnormal posture, tremor, and jerks occurring while writing with the opposite hand. A clinical case is presented, with videotape evidence of right-handed writer's cramp, with mirror movements elicited while writing using either hand. Functional magnetic resonance imaging studies are compared both to those of a normal patient and to those from a patient with writer's cramp but lacking mirror dystonia. Widespread bilateral activation of cortical motor areas contralateral to the mirror movements in patients with writer's cramp and mirror movements suggests, that bilateral activation of the primary motor cortex may account for the appearance of these mirror movements. Further studies need to be conducted to determine whether mirror movements in dystonic patients appear as a result of loss of intra- and/or interhemispheric cortical inhibition or are simply a consequence of the sustained effort these patients need to exert while writing using a dystonic hand. © 2005 Movement Disorder Society REFERENCES 1 Jedynak PC, Tranchant C, Zegers de Beyl D. Prospective clinical study of writer's cramp. Mov Disord 200; 16: 494– 499. 2 Marsden CD, Sheehy MP. Writer's cramp. TINS 1990; 13: 148– 153. 3 Marion MH, Afors K, Sheehy MP. Problems of treating writer's cramp with botulinum toxin injections: results from 10 years of experience. Rev Neurol (Paris) 2003; 159: 923– 927. 4 Siebner HR, Limmer C, Peinemann A, et al. Long-term consequences of switching handedness: a positron emission tomography study on handwriting in "converted" left-handers. J Neurosci 2002; 22: 2816– 2825. 5 Ceballos-Baumann AO, Sheean G, Passingham RE, et al. 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Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume21, Issue5May 2006Pages 683-689 ReferencesRelatedInformation
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