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Synthesis of 19-hydroxy LTB4, an assumed metabolite of leukotriene B4

1988; Elsevier BV; Volume: 29; Issue: 22 Linguagem: Inglês

10.1016/0040-4039(88)85249-3

1873-3581

Yves Le Merrer, Andreas Bonnet, Jean‐Claude Depezay,

Biochemical Analysis and Sensing Techniques

Abstract From D-mannitol, the total convergent synthesis of 19-hydroxy LTB4, an assumed metabolite of LTB4, has been carried out via α-hydroxyaldehydes. Connection at a four carbon atoms interval uses conjugated arsonium ylide.