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Is the Negri Body Specific for Rabies?

1975; American Medical Association; Volume: 32; Issue: 2 Linguagem: Inglês

10.1001/archneur.1975.00490440025002

1538-3687

Iraj Derakhshan,

Infectious Encephalopathies and Encephalitis

Since first described by Negri in 1903, the Negri body has been regarded as a pathognomonic finding in signifying the presence of rabies encephalitis. Negri bodies (light microscope) were found in the brain of a patient with conclusive evidence against the presence of rabies encephalitis. This case provided the opportunity for a pertinent review of the literature in bringing the subject into a reasoned perspective. A definitive etiologic diagnosis of rabies requires the use of electron microscopical or immunofluorescent methods or both.