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Neurofibroma in The Tongue: Case Report

2014; Elsevier BV; Volume: 117; Issue: 2 Linguagem: Inglês

10.1016/j.oooo.2013.12.132

2212-4411

José Narciso Rosa Assunção, José Narciso Rosa Assunção, JORGE DE SÁ BARBOSA, Haroldo Arid Soares, Nelise Alexandre da Silva Lascane, Décio dos Santos Pinto Júnior, Celso Augusto Lemos,

Tumors and Oncological Cases

Caucasian woman, 64, demonstrated a tongue lesion that had developed over 8 months. She reported local trauma with asymptomatic slow growth of a nodule. Intraoral examination showed an encapsulated submucosal nodule, measuring 1 cm in diameter, which was asymptomatic on palpation; the surface mucosa was reddish and smooth. The clinical diagnosis was neuroma X lipoma. After the excisional biopsy, histological examination revealed a mucosal fragment lined by stratified squamous epithelium and a parakeratinized area of dense connective tissue showing thick bundles of collagen fibers distributed parallel to the epithelium, with a proliferation of bundles of spindle cells in various directions, often with corrugated nuclei. There were also various stromal cells with eosinophilic cytoplasm resembling mast cells. The result suggested neurofibroma. The patient remains asymptomatic with no signs of recurrence after 1 year of follow-up.