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Rasmussen's encephalitis: an autoimmune disorder?

1996; Elsevier BV; Volume: 6; Issue: 5 Linguagem: Inglês

10.1016/s0959-4388(96)80102-4

1873-6882

P. Ian Andrews, James O McNamara,

Ion channel regulation and function

Rasmussen's encephalitis is a rare progressive pediatric epileptic syndrome. Recent evidence from experimental animals and patients with the disease suggests an important role for both humoral and cell-mediated immune mechanisms in the pathogenesis of this disease. The glutamate receptor subunit GluR3 may be an important autoantigen in the disease. (This review has been modified from a review published in Current Opinion in Neurology 1996, 9:141-145.)