Insights into Possible Skeletal Muscle Nicotinic Acetylcholine Receptor (AChR) Changes in Some Congenital Myasthenias from Physiological Studies, Point Mutations, and Subunit Substitutions of the AChRa
1993; Wiley; Volume: 681; Issue: 1 Linguagem: Inglês
10.1111/j.1749-6632.1993.tb22928.x
ISSN1749-6632
AutoresHenry J. Kaminski, Robert L. Ruff,
Tópico(s)Ion channel regulation and function
ResumoAnnals of the New York Academy of SciencesVolume 681, Issue 1 p. 435-450 Insights into Possible Skeletal Muscle Nicotinic Acetylcholine Receptor (AChR) Changes in Some Congenital Myasthenias from Physiological Studies, Point Mutations, and Subunit Substitutions of the AChRa HENRY J. KAMINSKI, HENRY J. KAMINSKI Departments of Neurology and Neuroscience, Department of Veterans Affairs Medical Center, Case Western Reserve University Medical School Cleveland, Ohio 44106Search for more papers by this authorROBERT L. RUFF, ROBERT L. RUFF Departments of Neurology and Neuroscience, Department of Veterans Affairs Medical Center, Case Western Reserve University Medical School Cleveland, Ohio 44106 Address inquiries to Robert L. Ruff, M.D., Ph.D., Department of Neurology 127(W), Department of Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland OH 44106.Search for more papers by this author HENRY J. KAMINSKI, HENRY J. KAMINSKI Departments of Neurology and Neuroscience, Department of Veterans Affairs Medical Center, Case Western Reserve University Medical School Cleveland, Ohio 44106Search for more papers by this authorROBERT L. RUFF, ROBERT L. RUFF Departments of Neurology and Neuroscience, Department of Veterans Affairs Medical Center, Case Western Reserve University Medical School Cleveland, Ohio 44106 Address inquiries to Robert L. Ruff, M.D., Ph.D., Department of Neurology 127(W), Department of Veterans Affairs Medical Center, 10701 East Boulevard, Cleveland OH 44106.Search for more papers by this author First published: June 1993 https://doi.org/10.1111/j.1749-6632.1993.tb22928.xCitations: 4 a This work was supported by Merit Reviewed Funding from the Department of Veterans Affairs, and National Institutes of Health Grants NS26661 and EY09186. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Engel, A. G., E. H. Lambert, D. M. Mulder, C. F. Torres, K. Sahashi, T. E. Bertorini & J. N. Whitaker. 1982. A newly recognized congenital myasthenic syndrome attributed to a prolonged open time of the acetylcholine-induced ion channel. Ann. Neurol. 11: 553–569. 2 Engel, A. G., T. J. Walls, A. Nagel & O. Uchitel. 1990. Newly recognized congenital myasthenic syndromes: I. Congenital paucity of synaptic vesicles and reduced quantal release. II. 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